Chip-based Evanescent Light Scattering (cELS) utilizes the multiple modes of a high-index contrast optical waveguide for near-field illumination of unlabeled samples, thereby repositioning the highest spatial frequencies of the sample into the far-field. The multiple modes scattering off the sample with different phase differences is engineered to have random spatial distributions within the integration ...

One strategy to combat antimicrobial resistance is the discovery of new classes of antibiotics. Most antibiotics will at some point interact with the bacterial membrane to either interfere with its integrity or to cross it. Reliable and efficient tools for determining the dissociation constant for membrane binding (K_<i>D</i>) and the partitioning coefficient between the aqueous- and ...

Identification of the seed varieties is essential in the quality control and high yield crop growth. The existing methods of varietal identification rely primarily on visual examination and DNA fingerprinting. Although the pattern of DNA fingerprinting allows precise classification of seed varieties but fraught with challenges such as low rate of polymorphism amongst closely related species, destructive ...

In 1934, Frits Zernike demonstrated that it is possible to exploit the sample’s refractive index to obtain superior contrast images of biological cells. The refractive index contrast of a cell surrounded by media yields a change in the phase and intensity of the transmitted light wave. This change can be due to either scattering or absorption caused by the sample. Most cells are transparent at visible ...

Objectives: Chronic wounds are characterised by prolonged inflammation, low mitogenic activity, high protease/low inhibitor activity, microbiota changes and biofilm formation, combined with the aetiology of the original insult. One strategy to promote healing is to terminate the parasitism-like relationship between the biofilm-growing pathogen and host response. Antimicrobial peptide AMC-109 is a ...

A Lagrangian snow-evolution model (SnowModel-LG) was used to produce daily, pan-Arctic, snow-on-sea-ice, snow property distributions on a 25 × 25-km grid, from 1 August 1980 through 31 July 2018 (38 years). The model was forced with NASA's Modern Era Retrospective-Analysis for Research and Applications-Version 2 (MERRA-2) and European Centre for Medium-Range Weather Forecasts (ECMWF) ReAnalysis-5th ...

Monitoring and surveillance changes around the world need powerful methods, so detection, visualization, and assessment of significant changes are essential for planning and management. Incorporating polarimetric SAR images due to interactions between electromagnetic waves and target and because of the high spatial resolution almost one meter can be used to study changes in the Earth's surface. Full ...

Abstract Afordable housing with fair and transparent land-allocation measures is a challenge for many countries. The Sultanate of Oman solves this issue by means of land-allocation lotteries in which male and female citizens can participate in order to win a parcel of a new housing area. Besides supporting those in fnancial need the lottery aims to mix the separate tribes of Oman and thus contribute ...

Swath bathymetry and chirp data have been used to investigate the submarine landform assemblages in inner Kongsfjorden, Svalbard, to reconstruct glacial dynamics during the Late Holocene. Multiple sets of landforms include two types of glacial lineations (groove-ridge features and small, drumlinoid ridges), terminal moraines and associated debris lobes, as well as small push moraines, and indicate ...

In this paper, we investigate overdetermined systems of scalar PDEs on the plane with one common characteristic, whose general solution depends on one function of one variable. We describe linearization of such systems and their integration via Laplace transformation, relating this to Lie's integration theorem and formal theory of PDEs.