Blar i utgivelsesdato Artikler, rapporter og annet (medisinsk biologi)
Viser treff 61-80 av 1054
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General practitioners' role in cancer care : a French-Norwegian study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009) -
Administration of tetradecylthioacetic acid (TTA) stimulates myocardial fatty acid oxidation despite having a lipid-lowering effect
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009) -
Genome-Wide Profile of Pleural Mesothelioma versus Parietal and Visceral Pleura : The emerging Gene Portrait of the Mesothelioma Phenotype
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009) -
Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW)F1 mice
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009) -
Silencing Viral MicroRNA as a Novel Antiviral Therapy?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-03-20)Viruses are intracellular parasites that ensure their existence by converting host cells into viral particle producing entities or into hiding places rendering the virus invisible to the host immune system. Some viruses may also survive by transforming the infected cell into an immortal tumour cell. MicroRNAs are small non-coding transcripts that function as posttranscriptional regulators of gene ... -
Prognostic Impact of Fibroblast Growth Factor 2 in NSCLC : Co-Expression with VEGFR-3 and PDGF-B Predicts Poor Survival
(Tidsskriftartikkel; Peer reviewed; Journal article, 2009-05)Purpose: Fibroblast growth factor 2 (FGF2; basic fibroblast growth factor, b-FGF) and its main receptor FGFR-1 are important in both hemangiogenesis and lymphangiogenesis. Murine studies have indicated a close interplay between both FGF2 and platelet-derived growth factor –B (PDGF-B) as well as FGF2 and vascular endothelial growth factor -3 (VEGFR-3). This study investigates the prognostic impact ... -
In vitro host range, multiplication and virion forms of recombinant viruses obtained from co-infection in vitro with a vaccinia-vectored influenza vaccine and a naturally occurring cowpox virus isolate
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-05-12)Background: Poxvirus-vectored vaccines against infectious diseases and cancer are currently under development. We hypothesized that the extensive use of poxvirus-vectored vaccine in future might result in co-infection and recombination between the vaccine virus and naturally occurring poxviruses, resulting in hybrid viruses with unpredictable characteristics. Previously, we confirmed that ... -
The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-06-15)Background: Cationic antimicrobial peptides (CAPs) with antitumor activity constitute a promising group of novel anticancer agents. These peptides induce lysis of cancer cells through interactions with the plasma membrane. It is not known which cancer cell membrane components influence their susceptibility to CAPs. We have previously shown that CAPs interact with the two glycosaminoglycans (GAGs), ... -
Binding site of ABC transporter homology models confirmed by ABCB1 crystal structure
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-09-04)The human ATP-binding cassette (ABC) transporters ABCB1, ABCC4 and ABCC5 are involved in resistance to chemotherapeutic agents. Here we present molecular models of ABCB1, ABCC4 and ABCC5 by homology based on a wide open inward-facing conformation of <i>Escherichia coli</i> MsbA, which were constructed in order to elucidate differences in the electrostatic and molecular features of their drug ... -
Matrix metalloproteinases in subjects with type 1 diabetes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-09-16)Background: Nephropathy is serious complication of diabetes. We have previously shown that level of the proteoglycan syndecan-1 in blood is associated with ultrastructural kidney changes in young persons with type 1 diabetes. Dysregulation of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) may contribute to the development of nephropathy. The aim of ... -
Metabolic syndrome in Russian adults : associated factors and mortality from cardiovascular diseases and all causes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
The RISAP-study : a complex intervention in risk communication and shared decision-making in general practice
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
The usefulness of immunohistochemistry in tissue microarrays of Human Papillomavirus negative adenocarcinoma of the uterine cervix
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
Dairy consumption and calcium intake and risk of breast cancer in a prospective cohort : The Norwegian Women and Cancer study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
Towards a more functional concept of causality in cancer research.
(Journal article; Tidsskriftartikkel, 2010) -
Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33 000 women from the general population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
Recruitment methods in Alzheimer's disease research : general practice versus population based screening by mail
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
Abdominal aortic aneurysms, or a relatively large diameter of non-aneurysmal aortas, increase total and cardiovascular mortality: the Tromsø study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)Background: In a population-based study in Tromsø, Norway, the authors assessed whether an abdominal aortic aneurysm (AAA) or the maximal infrarenal aortic diameter in a non-aneurismal aorta influence total and cardiovascular disease (CVD) mortality. Methods: A total of 6640 men and women, aged 25–84 years, were included in a 10-year mortality follow-up: 345 subjects with a diagnosed AAA and ... -
The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)