Blar i tittel Artikler, rapporter og annet (medisinsk biologi)

Viser treff 1038-1054 av 1054

    • What Do GPs Actually Know About Their Patients As Persons? 

      Mjølstad, Bente Prytz; Kirkengen, Anna Luise; Getz, Linn; Hetlevik, Irene (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-09-29)
      Background and Aims: Life experience and existential circumstances have an impact on health. Within medicine, however, the significance to patient care of person-related, biographical knowledge receives only rudimentary emphasis and its substantial theoretical underpinnings are inadequately understood and infrequently applied. This study explores the types and extent of some Norwegian general ...

    • What professional activities do general practitioners find most meaningful? Cross sectional survey of Norwegian general practitioners 

      Halvorsen, Peder Andreas; Edwards, A.; Aaraas, Ivar Johannes; Aasland, Olaf Gjerløw; Kristiansen, Ivar Sønbø (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Health reforms in many countries affect the scope and nature of primary care. General Practitioners (GPs) are expected to spend more time developing public health, preventive health care, coordination of care and teamwork. We aimed to explore which professional activities GPs consider to be meaningful and how they would like to prioritise tasks. In a cross sectional online survey 3,270 GPs were ...

    • 'When coercion moves into your home’ – a qualitative study of patient experiences with outpatient commitment in Norway 

      Riley, Henriette; Høyer, Georg; Lorem, Geir F (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      The use of coercion on people with mental health problems is a serious intervention, and a reduction in its use is a declared goal in mental healthcare. Yet, many countries have introduced expanded powers of coercion in recent years, including outpatient commitment (OC). However, the evidence of the effectiveness of OC is inconclusive, and little is known about how patients experience OC schemes. ...

    • When should acute exacerbations of COPD be treated with systemic corticosteroids and antibiotics in primary care: a systematic review of current COPD guidelines. 

      Laue, Johanna; Reierth, Eirik; Melbye, Hasse (Journal article; Tidsskriftartikkel, 2015)

    • Which Sámi? Sámi inclusion criteria in population-based studies of Sámi health and living conditions in Norway - an exploratory study exemplified with data from the SAMINOR study 

      Pettersen, Torunn; Brustad, Magritt (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: In a situation where national censuses do not record information on ethnicity, studies of the indigenous Sámi people’s health and living conditions tend to use varying Sámi inclusion criteria and categorizations. Consequently, the basis on which Sámi study participants are included and categorized when Sámi health and living conditions are explored and compared differs. This may influence ...

    • Whole transcriptome analysis of the Atlantic cod vaccine response reveals subtle changes in adaptive immunity 

      Solbakken, Monica Hongrø; Jentoft, Sissel; Reitan, Trond; Mikkelsen, Helene; Jakobsen, Kjetill Sigurd; Seppola, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-28)
      Atlantic cod has lost the Major Histocompatibility complex class II pathway – central to pathogen presentation, humoral response and immunity. Here, we investigate the immunological response of Atlantic cod subsequent to dip vaccination with <i>Vibrio anguillarum</i> bacterin using transcriptome sequencing. The experiment was conducted on siblings from an Atlantic cod family found to be highly ...

    • Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus heamolyticus in European hopsitals 

      Cavanagh, Jorunn Pauline; Hjerde, Erik; Holden, Matthew T.G.; Kahlke, Tim; Klingenberg, Claus; Flægstad, Trond; Parkhill, J; Bentley, Stephen D; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Whole-Organism Transcriptomic Analysis Provides Mechanistic Insight into the Acute Toxicity of Emamectin Benzoate in Daphnia magna 

      Song, You; Rundberget, Thomas; Evenseth, Linn Mari; Xie, Li; Gomes, Tania; Høgåsen, Tore; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-05)
      Emamectin benzoate (EMB) is an antisea lice chemical widely used in the aquaculture that may also unintentionally affect nontarget crustaceans in the environment. Although the adverse effects of this compound are well documented in various species, the full modes of action (MoAs) are still not well characterized. The current study was therefore conducted to characterize the MoAs of EMB and link ...

    • Why do women prefer home births in Ethiopia? 

      Shiferaw, Solomon; Spigt, Marcus; Godefrooij, Merijn; Melkamu, Yilma; Tekie, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Skilled attendants during labor, delivery, and in the early postpartum period, can prevent up to 75% or more of maternal death. However, in many developing countries, very few mothers make at least one antenatal visit and even less receive delivery care from skilled professionals. The present study reports findings from a region where key challenges related to transportation and ...

    • Why some women fail to give birth at health facilities: a qualitative study of women's perceptions of perinatal care from rural Southern Malawi 

      Kumbani, Lily C; Bjune, Gunnar Aksel; Chirwa, Ellen; Malata, Address; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Despite Malawi government’s policy to support women to deliver in health facilities with the assistance of skilled attendants, some women do not access this care. Objective: The study explores the reasons why women delivered at home without skilled attendance despite receiving antenatal care at a health centre and their perceptions of perinatal care. Methods: A descriptive study ...

    • Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17 

      Hetland, Marit; Hawkey, Jane; Bernhoff, Eva; Bakksjø, Ragna-Johanne; Kaspersen, Håkon; Rettedal, Siren; Sundsfjord, Arnfinn; Holt, Kathryn E.; Löhr, Iren Høyland (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-18)
      Klebsiella pneumoniae sequence type (ST) 17 is a global problem clone that causes multidrug-resistant (MDR) hospital infections worldwide. In 2008–2009, an outbreak of MDR ST17 occurred at a neonatal intensive care unit (NICU) in Stavanger, Norway. Fifty-seven children were colonized. We observed intestinal persistence of ST17 in all of the children for up to two years after hospital discharge. ...

    • Within-population distribution of trimethoprim resistance in Escherichia coli before and after a community-wide intervention on trimethoprim use 

      Sundqvist, Martin; Granholm, Susanne; Naseer, Mohammed Umaer; Rydén, Patrik; Brolund, Alma; Sundsfjord, Arnfinn; Kahlmeter, Gunnar; Johansson, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance 

      Wickström, Malin; Dyberg, Cecilia; Milosevic, Jelena; Einvik, Christer; Calero, Raul; Sveinbjørnsson, Baldur; Sandén, Emma; Darabi, Anna; Siesjö, Peter; Kool, Marcel; Kogner, Per; Baryawno, Ninib; Johnsen, John Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-25)
      The DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGMT) is commonly overexpressed in cancers and is implicated in the development of chemoresistance. The use of drugs inhibiting MGMT has been hindered by their haematologic toxicity and inefficiency. As a different strategy to inhibit MGMT we investigated cellular regulators of MGMT expression in multiple cancers. Here we show a ...

    • Women’s reproductive health in the Sakha Republic (Yakutia) 

      Douglas, Natalia I; Pavlova, Tatiana U; Burtseva, Tatiana E; Rad, Yana G; Petrova, Palmira G; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Zinc-Chelating Compounds as Inhibitors of Human and Bacterial Zinc Metalloproteases 

      Rahman, Fatema; Wushur, Imin; Malla, Nabin; Åstrand, Ove Alexander Høgmoen; Rongved, Pål; Winberg, Jan-Olof; Sylte, Ingebrigt (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-22)
      Inhibition of bacterial virulence is believed to be a new treatment option for bacterial infections. In the present study, we tested dipicolylamine (DPA), tripicolylamine (TPA), tris pyridine ethylene diamine (TPED), pyridine and thiophene derivatives as putative inhibitors of the bacterial virulence factors thermolysin (TLN), pseudolysin (PLN) and aureolysin (ALN) and the human zinc metalloproteases, ...

    • Zonda is a novel early component of the autophagy pathway in Drosophila 

      Melani, Mariana; Valko, Ayelen; Romero, Nuria M; Aguilera, Milton O; Acevedo, Julieta M; Bhujabal, Zambarlal; Perez-Perri, Joel; De La Riva-Carrasco, Rocio V; Katz, Maximiliano J; Sorianello, Eleonora; D'Alessio, Cecilia; Juhasz, Gabor; Johansen, Terje; Colombo, Maria I; Wappner, Pablo (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-13)
      Autophagy is an evolutionary conserved process by which eukaryotic cells undergo self-digestion of cytoplasmic components. Here we report that a novel Drosophila immunophilin, which we have named Zonda, is critically required for starvation-induced autophagy. We show that Zonda operates at early stages of the process, specifically for Vps34-mediated phosphatidylinositol 3-phosphate (PI3P) deposition. ...

    • β-lactam and fluoroquinolone resistance in Enterobacteriaceae from imported and locally-produced chicken in Mozambique 

      Faife, Sara Lino; Zimba, Tomas; Sekyere, John Osei; Govinden, Usha; Chenia, Hafizah Y.; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Essack, Sabiha (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-31)
      Introduction: Plasmid-mediated resistance to β-lactam and fluoroquinolone antibiotics was investigated in Enterobacteriaceae isolated from retailed frozen chickens from Brazil, South Africa and Mozambique.<p> <p>Methodology: Carcass swabs and the liquid thaw of 33 chickens from each of the three countries constituted the total sample size of 198. Isolates were identified by biochemical tests, ...