• Adjacent Disc Degeneration After Lumbar Total Disc Replacement or Non-operative Treatment: A Randomized Study With Eight-year Follow-up 

      Furunes, Håvard; Hellum, Christian; Espeland, Ansgar; Brox, Jens Ivar; Småstuen, Milada C; Berg, Linda; Storheim, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-15)
      <p><i>Study Design</i>: A randomized controlled multicenter trial with 8-year follow-up.</p> <p><i>Objective</i>: The aim of this study was to assess the long-term development of adjacent disc degeneration (ADD) after lumbar total disc replacement (TDR) or nonoperative treatment, and to analyze the association between ADD development and clinical outcome.</p> <p><i>Summary of Background ...
    • Adolescent self-harm and suicidal behavior and young adult outcomes in indigenous and non-indigenous people 

      Eckhoff, Christian; Sørvold, Maria Therene; Kvernmo, Siv (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-18)
      The aim of this study was to examine the associations between self-harm and suicidal behavior in indigenous Sami and non-Sami adolescents and mental health and social outcomes in young adulthood. Data were obtained by linking the Norwegian Patient Registry (2008–2012), the National Insurance Registry (2003–2013), and the Norwegian Arctic Adolescent Health Study, a school-based survey inviting all ...
    • Adoption of routine telemedicine in Norway: The current picture 

      Zanaboni, Paolo; Knarvik, Undine; Wootton, Richard (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Adoption of telemedicine : from pilot stage to routine delivery 

      Zanaboni, Paolo; Wootton, Richard (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Today there is much debate about why telemedicine has stalled. Teleradiology is the only widespread telemedicine application. Other telemedicine applications appear to be promising candidates for widespread use, but they remain in the early adoption stage. The objective of this debate paper is to achieve a better understanding of the adoption of telemedicine, to assist those trying to move applications ...
    • Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis 

      Hudson, Jemma; Cruickshank, Moira; Quinton, Richard; Aucott, Lorna; Aceves-Martins, Magaly; Gillies, Katie; Bhasin, Shalender; Snyder, Peter J; Ellenberg, Susan S; Grossmann, Mathis; Travison, Thomas G; Gianatti, Emily J; van der Schouw, Yvonne T; Emmelot-Vonk, Marielle H; Giltay, Erik J; Hackett, Geoff; Ramachandran, Sudarshan; Svartberg, Johan; Hildreth, Kerry L; Groti Antonic, Kristina; Brock, Gerald B; Tenover, J Lisa; Tan, Hui Meng; Kong, Christopher Ho Chee; Tan, Wei Shen; Marks, Leonard S; Ross, Richard J; Schwartz, Robert S; Manson, Paul; Roberts, Stephen; Andersen, Marianne; Magnussen, Line Velling; Hernández, Rodolfo; Oliver, Nick; Wu, Frederick; Dhillo, Waljit S; Bhattacharya, Siladitya; Brazzelli, Miriam; Jayasena, Channa N (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-09)
      Background Testosterone is the standard treatment for male hypogonadism, but there is uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide the most extensive individual participant dataset (IPD) of testosterone trials available, to analyse subtypes of all cardiovascular events observed during treatment, and to investigate the effect of incorporating data ...
    • Adverse events in hospitalised cancer patients: a comparison to a general hospital population 

      Haukland, Ellinor Christin; von Plessen, Christian; Nieder, Carsten; Vonen, Barthold (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-05)
      <p><i>Background</i>: Patients with cancer are often treated by many healthcare providers, receive complex and potentially toxic treatments that can increase the risk for iatrogenic harm. The aim of this study is to investigate whether hospitalised cancer patients are at higher risk of adverse events (AEs) compared to a general hospital population.</p> <p><i>Material and methods</i>: A total of ...
    • Adverse events reporting by obstetric units in Norway as part of their quality assurance and patient safety work: an analysis of practice 

      Johansen, Lars Thomas; Braut, Geir Sverre; Acharya, Ganesh; Andresen, Jan Fredrik; Øian, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
      Background - The Norwegian Board of Health Supervision aims to contribute to the improvement of quality and patient safety in the healthcare services. Planned audits were performed to investigate how 12 selected Norwegian obstetric units reported and analyzed adverse events as the part of their quality assurance and patient safety work.<p> Methods - Serious adverse events coded as birth asphyxia, ...
    • Against All Odds? Sami Women’s Lower NEET Experience in An Arctic Context: Education and Work Participation among Multicultural Young People in Northern-Norway, the Norwegian Arctic Adolescent Health Study (NAAHS) 

      Bania, Elisabeth Valmyr; Eckhoff, Christian; Ekornes, Stine M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-25)
      The present paper explores Sami women’s lower NEET (Not engaged in Education, Employment or Training) experience in an ethnoreligious multicontext perspective. Data are derived from a cross-sectional cohort and registry follow-up study in Northern Norway, 2003–2012, and data from Statistics Norway are included for an up-to date data analysis (2021). This is a cross-sectional cohort and registry data ...
    • Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population 

      Gaya de Costa, Mariana; Poppelaars, Felix; van Kooten, Cees; Mollnes, Tom Eirik; Tedesco, Francesco; Würzner, Reinhard; Trouw, Leendert A.; Truedsson, Lennart; Daha, Mohamed R.; Roos, Anja; Seelen, Marc A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-20)
      <p><i>Introduction</i>: The complement system is essential for an adequate immune response. Much attention has been given to the role of complement in disease. However, to better understand complement in pathology, it is crucial to first analyze this system under different physiological conditions. The aim of the present study was therefore to investigate the inter-individual variation in complement ...
    • Agreement between anatomical M-mode and tissue Doppler imaging in the assessment of fetal atrioventricular annular plane displacement in uncomplicated pregnancies: A prospective longitudinal study 

      Zanardini, Cristina; D'Antonio, Francesco; Hvingel, Bodil; Vårtun, Åse; Prefumo, Federico; Flacco, Maria E.; Manzoli, Lamberto; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-23)
      Aim To evaluate the level of agreement between M‐mode and pulsed‐wave tissue Doppler imaging (PW‐TDI) techniques in assessing fetal mitral annular plane systolic excursion (MAPSE), tricuspid annular plane systolic excursion (TAPSE) and septal annular plane systolic excursion (SAPSE) in a low‐risk population. Methods This prospective longitudinal study included healthy fetuses assessed from 18 to ...
    • Agreement between preload reserve measured by impedance cardiography and echocardiography during pregnancy 

      Liang, Huan; Vårtun, Åse; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-05)
      <i>Purpose</i>: Accurate assessment of cardiac function is important during pregnancy. Echocardiography and impedance cardiography (ICG) are commonly used noninvasive methods to measure stroke volume (SV) and cardiac output (CO). The diference in stroke volume (ΔSV) or cardiac output (ΔCO) measured at baseline and after passive leg raising (PLR) is a measure of preload reserve that predicts volume ...
    • Agreement on web-based diagnoses and severity of mental health problems in Norwegian child and adolescent mental health services 

      Brøndbo, Per Håkan; Mathiassen, Børge Idar; Martinussen, Monica; Heiervang, Einar; Eriksen, Mads; Kvernmo, Siv (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Objective: This study examined the agreement between diagnoses and severity ratings assigned by clinicians using a structured web-based interview within a child and adolescent mental health outpatient setting. Method: Information on 100 youths was obtained from multiple informants through a web-based Development and Well-Being Assessment (DAWBA). Based on this information, four experienced ...
    • Air ambulance flights in northern Norway 2002- 2008. Increased number of secondary fixed wing (FW) operations and more use of rotor wing (RW) transports 

      Norum, Jan; Elsbak, Trond M (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Air ambulance service in Norway has been upgraded during the last years. European regulations concerning pilots’ working time and new treatment guidelines/strategies have called for more resources. The objective was to describe and analyse the two supplementary air ambulance [fixed wing (FW) and rotor wing (RW)] alternatives’ activity during the study period (2002-2008). Furthermore we aimed to ...
    • Air ambulance nurses as expert supplement to local emergency services 

      Wisborg, Torben; Bjerkan, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-12-25)
      Introduction: Flight nurses in the Norwegian National Air Ambulance Service are specialist nurse anesthetists or intensive care nursing specialists. For air ambulance bases far from hospitals, these nurses represent otherwise unavailable competencies. This study reports a 6-year experience with flight nurse participation in local emergencies beyond the transportation phase. <br>Methods: The ...
    • Air ambulance services in the Arctic 1999-2009 : a Norwegian study. 

      Norum, Jan; Elsbak, Trond M (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Air ambulance services in the Arctic have to deal with remote locations, long distances, rough weather conditions and seasonable darkness. Despite these challenges, the people living in the area expect a high quality of specialist health care. The objective of this study was to analyse the air ambulance operations performed in the Norwegian Arctic and study variations in diagnoses and flight patterns ...
    • Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood 

      Storm, Benjamin; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Lau, Corinna; Lambris, John D.; Woodruff, Trent M.; Brekke, Ole-Lars; Braaten, Tonje Bjørndal; Nielsen, Erik Waage; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-03)
      Venous air embolism, which may complicate medical and surgical procedures, activates complement and triggers thromboinflammation. In lepirudin-anticoagulated human whole blood, we examined the effect of air bubbles on complement and its role in thromboinflammation. Whole blood from 16 donors was incubated with air bubbles without or with inhibitors of C3, C5, C5aR1, or CD14. Complement activation, ...
    • Airway management by physician-staffed Helicopter Emergency Medical Services – a prospective, multicentre, observational study of 2,327 patients 

      Sunde, Geir Arne; Heltne, Jon-Kenneth; Lockey, David; Burns, Brian; Sandberg, Mårten; Fredriksen, Knut; Hufthammer, Karl Ove; Soti, Akos; Lyon, Richard; Jäntti, Helena; Kämäräinen, Antti; Reid, Bjørn Ole; Silfvast, Tom; Harm, Falko; Sollid, Stephen J. M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-07)
      <p>Background: Despite numerous studies on prehospital airway management, results are difficult to compare due to inconsistent or heterogeneous data. The objective of this study was to assess advanced airway management from international physician-staffed helicopter emergency medical services. <p>Methods: We collected airway data from 21 helicopter emergency medical services in Australia, England, ...
    • Alanine aminotransferase and body composition in obese men and women 

      Bekkelund, Svein Ivar; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-26)
      There is a known relationship between serum alanine aminotransferase (ALT) and obesity in humans, but the mechanism(s) are not clarified. This study investigated the associations between serum ALT and body composition in an overweight and obese population. The results are based on data from a previous randomized controlled trial treating obesity with vitamin D<sub>3</sub>. A sample of 448 overweight ...
    • ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial 

      Ueland, Thor; Åkerblom, Axel; Ghukasyan, Tatevik; Michelsen, Annika; Becker, Richard C; Bertilson, Maria; Budaj, Andrzej; Cornel, Jan H; Himmelmann, Anders; James, Stefan K; Siegbahn, Agneta; Storey, Robert F; Kontny, Frederic; Aukrust, Pål; Wallentin, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-29)
      <p><i>Background and aims - </i>Activated leukocyte cell adhesion molecule (ALCAM) is upregulated during inflammation and involved in transmigration of leukocytes and T-cell activation. We hypothesized that ALCAM might be associated with recurrent events in patients with acute coronary syndromes (ACS). <p><i>Methods - </i>ALCAM was measured in serum obtained on admission, at discharge, 1 month and ...
    • Alcohol consumption and common carotid intima-media thickness: The USE-IMT study 

      Britton, Annie R.; Grobbee, Diederick E.; den Ruijter, Hester M.; Anderson, Todd J.; Desvarieux, Moise; Engström, Gunnar; Evans, Greg W.; Hedblad, Bo; Kauhanen, Jussi; Kurl, Sudhir; Lonn, Eva M.; Mathiesen, Ellisiv B.; Polak, Joseph F.; Price, Jacqueline F.; Rembold, Christopher M.; Rosvall, Maria; Rundek, Tatjana; Salonen, Jukka T.; Stehouwer, Coen; Tuomainen, Tomi-Pekka; Bots, Michiel L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-19)