Blar i tittel Artikler, rapporter og annet (klinisk medisin)

Viser treff 529-548 av 1796

    • Efficacy of chronic pre-emptive rituximab treatment in ANCA-associated vasculitis 

      Besada, Emilio; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)

    • Electronic Health Use in a Representative Sample of 18,497 Respondents in Norway (The Seventh Tromsø Study - Part 1): Population-Based Questionnaire Study 

      Wynn, Rolf; Oyeyemi, Sunday Oluwafemi; Budrionis, Andrius; Ruiz, Luis Marco; Yigzaw, Kassaye Yitbarek; Bellika, Johan Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-05)
      <p><i>Background:</i> Electronic health (eHealth) services may help people obtain information and manage their health, and they are gaining attention as technology improves, and as traditional health services are placed under increasing strain. We present findings from the first representative, large-scale, population-based study of eHealth use in Norway. <p><i>Objective:</i> The objectives of ...

    • Electronic Symptom Reporting Between Patient and Provider for Improved Health Care Service Quality: A Systematic Review of Randomized Controlled Trials. Part 1: State of the Art 

      Johansen, Monika Alise; Henriksen, Eva; Horsch, Alexander; Schuster, Tibor; Berntsen, Gro (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Background: Over the last two decades, the number of studies on electronic symptom reporting has increased greatly. However, the field is very heterogeneous: the choices of patient groups, health service innovations, and research targets seem to involve a broad range of foci. To move the field forward, it is necessary to build on work that has been done and direct further research to the areas holding ...

    • Electronic Symptom Reporting Between Patient and Provider for Improved Health Care Service Quality: A Systematic Review of Randomized Controlled Trials. Part 2: Methodological Quality and Effects 

      Johansen, Monika Alise; Berntsen, Gro; Schuster, Tibor; Henriksen, Eva; Horsch, Alexander (Tidsskriftartikkel; Journal article; Peer reviewed, 2012)
      Background: We conducted in two parts a systematic review of randomized controlled trials (RCTs) on electronic symptom reporting between patients and providers to improve health care service quality. Part 1 reviewed the typology of patient groups, health service innovations, and research targets. Four innovation categories were identified: consultation support, monitoring with clinician support, ...

    • Electrosurgery and temperature increase in tissue with a passive metal implant 

      Martinsen, Tormod; Pettersen, Fred-Johan; Kalvøy, Håvard; Tronstad, Christian; Kvarstein, Gunnvald; Bakken, André; Høgetveit, Jan Olav; Martinsen, Ørjan Grøttem; Grimnes, Sverre; Frich, Lars Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-12)
      <i>Importance</i>: During monopolar electrosurgery in patients, current paths can be influenced by metal implants, which can cause unintentional tissue heating in proximity to implants. Guidelines concerning electrosurgery and active implants such as pacemakers or implantable cardioverter defibrillators have been published, but most describe interference between electrosurgery and the active implant ...

    • Elevated blood pressure is not associated with accelerated glomerular filtration rate decline in the general non-diabetic middle-aged population 

      Eriksen, Bjørn Odvar; Stefansson, Vidar Tor Nyborg; Jenssen, Trond Geir; Mathisen, Ulla Dorte; Schei, Jørgen; Solbu, Marit Dahl; Wilsgaard, Tom; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-14)
      Although hypertension is a risk factor for end-stage renal disease, this complication develops in only a minority of hypertensive patients. Whether non-malignant hypertension itself is sufficient to cause reduced glomerular filtration rate (GFR) is unclear. We investigated whether elevated blood pressure (BP) was associated with accelerated GFR decline in the general population. The study ...

    • Elevated cholesteryl ester transfer protein activity early in pregnancy predicts prediabetes 5 years later 

      Ueland, Thor; Roland, Marie Cecilie; Michelsen, Annika; Godang, Kristin; Aukrust, Pål; Henriksen, Tore; Bollerslev, Jens; Lekva, Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-29)
      <i>Context</i> - Cholesteryl ester transfer protein (CETP) regulates high-density lipoprotein (HDL) cholesterol levels and interaction between glucose, and HDL metabolism is central in the development of diabetes.<p> <p><i>Objective</i> - We hypothesized that CETP levels would be regulated in diabetic pregnancies. We tested the hypothesis by evaluating CETP activity measured multiple times during ...

    • Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism 

      Iglesias, Maria Jesus; Sanchez-Rivera, Laura; Ibrahim-Kosta, Manal; Naudin, Clément; Munsch, Gaëlle; Goumidi, Louisa; Farm, Maria; Smith, Philip M.; Thibord, Florian; Kral-Pointner, Julia Barbara; Hong, Mun-Gwan; Suchon, Pierre; Germain, Marine; Schottmaier, Waltraud; Dusart, Philip James; Boland, Anne; Kotol, David; Edfors, Fredrik; Koprulu, Mine; Pietzner, Maik; Langenberg, Claudia; Damrauer, Scott M.; Johnson, Andrew D.; Klarin, Derek M.; Smith, Nicholas L.; Smadja, David M.; Holmström, Margareta; Magnusson, Maria; Silveira, Angela; Uhlén, Mathias; Renné, Thomas; Martinez-Perez, Angel; Emmerich, Joseph; Deleuze, Jean-Francois; Antovic, Jovan; Soria Fernandez, Jose Manuel; Assinger, Alice; Schwenk, Jochen M.; Souto Andres, Joan Carles; Morange, Pierre-Emmanuel; Butler, Lynn; Trégouët, David-Alexandre; Odeberg, Jacob (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-07)
      Venous thromboembolism (VTE) is a common, multi-causal disease with potentially serious short- and long-term complications. In clinical practice, there is a need for improved plasma biomarker-based tools for VTE diagnosis and risk prediction. Here we show, using proteomics profiling to screen plasma from patients with suspected acute VTE, and several case-control studies for VTE, how Complement ...

    • Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism 

      Skjeflo, Espen Waage; Brækkan, Sigrid Kufaas; Ludviksen, Judith K; Snir, Omri; Hindberg, Kristian; Mollnes, Tom Eirik; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      The role of complement in the pathogenesis of venous thromboembolism (VTE) is unclear. We wanted to investigate (1) whether plasma complement component C5 (C5) levels are influenced by genetic variants or chronic inflammation and (2) the association between plasma C5 and risk of future VTE in a nested case-control study of 415 patients with VTE and 848 age- and sex-matched controls derived from the ...

    • Elevated plasma D-dimer levels are associated with risk of future incident venous thromboembolism 

      Hansen, Ellen-Sofie; Rinde, Fridtjof Balteskard; Edvardsen, Magnus; Hindberg, Kristian; Latysheva, Nadezhda; Aukrust, Pål; Ueland, Thor; Michelsen, Annika Elisabet; Hansen, John Bjarne; Brækkan, Sigrid Kufaas; Morelli, Vania Maris (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-25)
      <p><i>Background</i> D-dimer, a global biomarker for activation of the coagulation and fibrinolysis systems, is useful in assessing individual risk of venous thromboembolism (VTE) recurrence. However, there is limited information on the association between D-dimer and risk of a first lifetime VTE event. <p><i>Objectives</i> To investigate the association between plasma D-dimer levels and risk of ...

    • Elevated Plasma Levels of P‐Selectin Glycoprotein Ligand‐1 Positive Microvesicles in Patients with Unprovoked Venous Thromboembolism 

      Jamaly, Simin; Basavaraj, Manjunath Goolyam; Starikova, Irina; Olsen, Randi; Brækkan, Sigrid K.; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-31)
      Background<br> Microvesicles (MVs) express antigens from their parental cells and have a highly procoagulant surface. Animal studies suggest that P‐Selectin Glycoprotein Ligand‐1 positive (PSGL‐1+) MVs play a role in the pathogenesis of venous thromboembolism (VTE).<p> Objective<br> The aim of this study was to determine plasma levels, the cellular origin and the morphological characteristics ...

    • Embodied health practices:The use of Traditional Healing and Conventional Medicine in a North Norwegian Community 

      Kiil, Mona Anita; Salamonsen, Anita (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-11)
      Scandinavian welfare states like Norway represent a cultural context in which citizens who become ill are supposed to trust and receive health care within the conventional health care system that is officially subsidized and based on biomedical knowledge. Despite this officially initiated health practice, unofficial and non-commercial health practices exist in many North Norwegian communities, ...

    • En kvinne med feber, røde øyne og utbredt utslett. 

      Bremnes, Øyvind; Grimstad, Øystein; Bremnes, Katja (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-08)
      En kvinne i 70-årene ble innlagt i medisinsk avdeling med spørsmål om allergi. Hun hadde feber, frostanfall, muskel- og leddsmerter, kløende utslett og bilateral konjunktival injeksjon. Det ble en langvarig innleggelse med et livstruende forløp.

    • En mann i 40-årene med akutt forvirring 

      Karlberg, Merethe; Thoresen, Hanne; Berg, Diana Hristova; Ciopat, Oana-Gratiela; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-07)
      Rask og adekvat utredning av akutte nevropsykiatriske symptomer er avgjørende for effektiv behandling. Her beskriver vi en pasient med en karakteristisk, men relativt sjelden sykdom.

    • Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning 

      Paulsen, Else Quist; Ormaasen, Vidar; Kran, Anne-Marte Bakken; Dunlop, Oona Borghild; Ueland, Per Magne; Ueland, Thor; Eikeland, Randi; Aukrust, Pål; Nordenmark, Tonje Haug (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-06)
      For those surviving encephalitis, the influence on daily life of patients and their relatives may be substantial. In contrast, the prognosis after aseptic meningitis (ASM) is considered good. In this prospective study in patients with encephalitis (n = 20) and ASM (n = 46), we show that both groups experienced reduced Health Related Quality of Life (HRQoL) at two months after discharge, and that ...

    • Endometrial receptivity in women of advanced age: an underrated factor in infertility 

      Pathare, Amruta D.S.; Loid, Marina; Saare, Merli; Gidlöf, Sebastian Brusell; Esteki, Masoud Zamani; Acharya, Ganesh Prasad; Peters, Maire; Salumets, Andres (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-19)
      BACKGROUND Modern lifestyle has led to an increase in the age at conception. Advanced age is one of the critical risk factors for female-related infertility. It is well known that maternal age positively correlates with the deterioration of oocyte quality and chromosomal abnormalities in oocytes and embryos. The effect of age on endometrial function may be an equally important factor influencing ...

    • Endothelial function after pancreas transplantation - A single-center observational study 

      Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
      <i>Background</i> - Patients with diabetes mellitus treated with successful pancreas transplantation (PTX) normalize hyperglycemia, but are exposed to immunosuppressive drugs that may impair endothelial function. This study aimed to evaluate endothelial function in single PTX recipients.<p><p> <i>Methods</i> - Flow‐mediated dilatation (FMD) in the brachial artery was measured by ultrasound 8 weeks ...

    • Endothelin-1 stimulates human monocytes in vitro to release TNF-α, IL-1β and IL-6 

      Helset, E.; Sildnes, T.; Seljelid, R.; Konopski, Z. S. (Journal article; Tidsskriftartikkel; Peer reviewed, 1993-09-09)
      INCREASED plasma- and tissue levels of endothelin-1 (ET-1) during inflammatory diseases, have suggested a role of ET-1 in the pathophysiology of inflammatory reactions. The authors have studied the effect of ET-1 on cytokine release from monocytes and monocyte-derived macrophages. ET-1 increased secretion of TNF-α, IL-1β and IL-6 in a dose- and time-dependent manner. Optimal ET-1 concentration ...

    • Endothelin-1 Stimulates Monocytes in vitro to Release Chemotactic Activity Identified as Interleukin-8 and Monocyte Chemotactic Protein-1 

      Helset, E.; Sildnes, T.; Konopski, Z. S. (Journal article; Tidsskriftartikkel; Peer reviewed, 1994)
      In the present study we examined whether endothelin-1 stimulation of human monocytes causes release of chemotactic factors. It was found that monocytes released neutrophil- and monocyte-chemotactic activity in a dose- and time-dependent manner in response to ET-1. ET-1 did not show any chemotactic activity by itself. NCA was detected in monocyte supernatants in response to ET-1 (0.01–100 nM) after ...

    • Endotoxin removal in septic shock with the Alteco LPS Adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial - the Asset Study 

      Lipcsey, Miklos; Tenhunen, Jyrki; Pischke, Soeren; Kuitunen, Anne; Flaatten, Hans; De Geer, Lina; Sjölin, Jan; Frithiof, Robert; Chew, Michelle S.; Bendel, Stepani; Kawati, Rafael; Larsson, Anders; Mollnes, Tom Eirik; Tønnessen, Tor Inge; Rubertsson, Sten (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08)
      <i>Purpose</i>: Lipopolysaccharides (LPS) are presumed to contribute to the inflammatory response in sepsis. We investigated if extracorporeal Alteco LPS Adsorber for LPS removal in early gram-negative septic shock was feasible and safe. Also, effects on endotoxin level, inflammatory response, and organ function were assessed.<br><br> <i>Methods</i>: A pilot, double-blinded, randomized, Phase ...