Viser treff 773-792 av 1796

    • Human blood serum proteome changes after 6 hours of sleep deprivation at night 

      Bjørkum, Alvhild Alette; Duran, Ana Carasco; Roy, Dola Sinha; Rosendahl, Karen; Birkeland, Even; Stuhr, Linda Elin Birkhaug (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-25)
      Background: The aim of this study was to discover significantly changed proteins in human blood serum after loss of 6 h sleep at night. Furthermore, to reveal affected biological process- and molecular function categories that might be clinically relevant, by exploring systems biological databases.<p> <p>Methods: Eight females were recruited by volunteer request. Peripheral venous whole blood was ...
    • Human endogenous retrovirus W Activity in cartilage of osteoarthritis patients 

      Bendiksen, Signy; Martinez, Inigo Zubiavrre; Tümmler, Conny; Knutsen, Gunnar; Elvenes, Jan; Olsen, Elisabeth; Olsen, Randi; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Hva styrker verdigheten til kreftsyke kvinner som ønsker å dø hjemme? 

      Staats, Katrine; Tranvåg, Oscar; Grov, Ellen Karine (Journal article; Tidsskriftartikkel, 2019-05-15)
      Når pasienter ønsker å dø hjemme er det viktig at hjemmesykepleiere har god kompetanse i bruken av symptomlindrende legemidler. Hensikten med studien er å utvikle ny kunnskap om hjemmesykepleieres erfaringer med å bruke medikamentskrin i symptomlindrende omsorg for hjemmeboende pasienter i terminalfase. Vi presenterer faktorer som skaper trygghet og fremmer bruken av medikamentskrinet, i tillegg til ...
    • Hvordan forbedre? 

      Joakimsen, Peder (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-13)
      Hei, det er vanskelig ut fra innlegget å se hva som faktisk skal kunne bidra til en «bredere rekrutteringsbase»
    • Hyperglycemia, Assessed by HbA1c, and Future Risk of Venous Thromboembolism - The Tromsø Study 

      Lerstad, Gunhild; Brodin, Ellen Elisabeth; Enga, Kristin; Jorde, Rolf; Schirmer, Henrik; Njølstad, Inger; Svartberg, Johan; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-03-05)
      Background: Glycated hemoglobin (HbA1c), a marker of average plasma glucose during the last 8-12 weeks, is associated with future risk of cardiovascular disease (CVD) and all-cause mortality. Objectives: To examine the association between hyperglycemia, assessed by HbA1c, and future risk of VTE in a population based cohort. Methods: HbA1c was measured in 16 156 unique subjects (25-87 years) ...
    • Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis 

      Gundersen, Mona Dixon; Larsen, Kenneth Bowitz; Johnsen, Kay-Martin; Goll, Rasmus; Florholmen, Jon; Haraldsen, Guttorm (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-07)
      Epithelial alarmins are gaining interest as therapeutic targets for chronic infammation. The nuclear alarmin interleukin-33 (IL-33) is upregulated in the colonic mucosa of acute ulcerative colitis (UC) and may represent an early instigator of the infammatory cascade. However, it is not clear what signals drive the expression of IL-33 in the colonic mucosa, nor is the exact role of IL-33 elucidated. We ...
    • Hypocomplementemia as a Risk Factor for Organ Damage Accrual in Patients with Systemic Lupus Erythematosus 

      Raymond, Warren David; Eilertsen, Gro Østli; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-30)
      While it is a common practice to monitor complement levels in patients with systemic lupus erythematosus to aid in flare prediction and detection, it is unclear if this strategy is helpful in preventing subsequent organ damage. We studied longitudinal complement levels in 102 SLE patients during a median follow-up of 13.8 years (IQR 7.0, 23.1). Low complement was defined as C3 < 0.84 g/L and/or ...
    • Hypothermia and cardiac electrophysiology: a systematic review of clinical and experimental data 

      Dietrichs, Erik Sveberg; Tveita, Torkjel; Smith, Godfrey L (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-13)
      Moderate therapeutic hypothermia procedures are used in post-cardiac arrest care, while in surgical procedures, lower core temperatures are often utilized to provide cerebral protection. Involuntary reduction of core body temperature takes place in accidental hypothermia and ventricular arrhythmias are recognized as a principal cause for a high mortality rate in these patients. We assessed both ...
    • Hypothermic cardiac arrest far away from the center providing rewarming with extracorporeal circulation. 

      Mark, Eckhard; Jacobsen, Olaf; Kjerstad, Astrid Kristine; Næsheim, Torvind; Busund, Rolf; Bahar, Ramez; Jensen, Jon Kjetil; Skorpen, Per Kristian; Bjertnæs, Lars J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      A 41-year-old man suffered hypothermic cardiac arrest after water immersion and was transported to our university hospital by ambulance helicopter for rewarming on cardiopulmonary bypass. He resumed spontaneous cardiac activity 6 h 52 min after cardiac arrest and recovered completely.
    • Hypoxia and hypotension in patients intubated by physician staffed helicopter emergency medical services - a prospective observational multi-centre study 

      Sunde, Geir Arne; Sandberg, Mårten; Lyon, Richard; Fredriksen, Knut; Burns, Brian; Hufthammer, Karl Ove; Røislien, Jo; Sóti, Ákos; Jäntti, Helena; Lockey, David; Heltne, Jon-Kenneth; Sollid, Stephen J. M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-11)
      The effective treatment of airway compromise in trauma and non-trauma patients is important. Hypoxia and hypotension are predictors of negative patient outcomes and increased mortality, and may be important quality indicators of care provided by emergency medical services. Excluding cardiac arrests, critical trauma and non-trauma patients remain the two major groups to which helicopter emergency ...
    • Hysterektomi ved kraftige menstruasjonsblødninger: forenklet metodevurdering 

      Evensen, Line Holtet; Espeland, Anna Lien; Ashtiani, Vida Hamidi; Risstad, Hilde; Elvsaas, Ida-Kristin Ørjasæter (Research report; Forskningsrapport, 2021-06-10)
      Vi har på oppdrag fra Bestillerforum for nye metoder utarbeidet en forenklet metodevurdering om hysterektomi (kirurgisk fjerning av livmor) ved kraftige menstruasjonsblødninger. Dette er en pilot i et prosjekt innen revurdering som ledes av Helse Midt-Norge RHF. Vi har hentet ut resultater for effekt og sikkerhet og vurderinger av tillit til resultatene for effekt fra en rapport av The National ...
    • Høyt nivå av tungmetaller i krabbe 

      Averina, Maria; Monsen, Anne-Lise Bjørke; Bolann, Bjørn Johan; Brox, Jan; Eggesbø, Merete; Hokstad, Ingrid; Huber, Sandra; Ørebech, Peter Th (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)
      Krabber er populær sjømat, men kan inneholde til dels store mengder miljøgifter. Innholdet er mange steder i Norge så høyt at inntak av brunmaten generelt bør frarådes.
    • I don’t want to think about it: A qualitative study of children’s and parents’ experiences with regular needle injections at home 

      Sørensen, Kari; Skirbekk, Helge; Kvarstein, Gunnvald; Wøien, Hilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-22)
      <i>Background</i> - Overall outcomes of pediatric rheumatic diseases (RD) have improved due to treatment with biologic agents and methotrexate. For many children, this treatment often entails regular needle injections. Pain and fear of needle injections are common in childhood, but how children and parents handle long-term needle injections at home has not been fully explored. This study aimed to ...
    • Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies 

      Marsh, Phillip L.; Moore, Ernest E.; Moore, Hunter B.; Bunch, Connor M.; Aboukhaled, Michael; Condon, Shaun M.; Al-Fadhl, Mahmoud D.; Thomas, Samuel J.; Larson, John R.; Bower, Charles W.; Miller, Craig B.; Pearson, Michelle L.; Twilling, Christopher L.; Reser, David W.; Kim, George S.; Troyer, Brittany M.; Yeager, Doyle; Thomas, Scott G.; Srikureja, Daniel P.; Patel, Shivani S.; Añón, Sofía L.; Thomas, Anthony V.; Miller, Joseph B.; Van Ryn, David E.; Pamulapati, Saagar V.; Zimmerman, Devin; Wells, Byars; Martin, Peter L.; Seder, Christopher W.; Aversa, John G.; Greene, Ryan B.; March, Robert J.; Kwaan, Hau C.; Fulkerson, Daniel H.; Vande Lune, Stefani A.; Mollnes, Tom Eirik; Nielsen, Erik Waage; Stage Storm, Benjamin; Walsh, Mark M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-19)
      Iatrogenic vascular air embolism is a relatively infrequent event but is associated with significant morbidity and mortality. These emboli can arise in many clinical settings such as neurosurgery, cardiac surgery, and liver transplantation, but more recently, endoscopy, hemodialysis, thoracentesis, tissue biopsy, angiography, and central and peripheral venous access and removal have overtaken surgery ...
    • ICU nurses´ lived experience of caring for adult patients with a tracheostomy in ICU: a phenomenological-hermeneutic study 

      Akroute, Abder Rahim; Brinchmann, Berit Støre; Hovland, Anders Wilhelm; Fredriksen, Sven-Tore Dreyer (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-04)
      <b><p>Background</b> The care of adult patients with a tracheostomy in intensive care unit is complex, challenging and requires skilled intensive care unit nurses. ICU nurses’ live experience is scarcely known. This study aimed to describe the lived experience of intensive care unit nurses of caring for adult patients with a tracheostomy in intensive care unit. <b><p>Methods</b> This study ...
    • Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant 

      Wang, Qiang; Martínez-Bonet, Marta; Kim, Taehyeung; Sparks, Jeffrey A.; Ishigaki, Kazuyoshi; Chen, Xiaoting; Sudman, Marc; Aguiar, Vitor; Sim, Sangwan; Hernandez, Marcos Chiñas; Chiu, Darren J.; Wactor, Alexandra; Wauford, Brian; Marion, Miranda C.; Gutierrez-Arcelus, Maria; Bowes, John; Eyre, Stephen; Nordal, Ellen Berit; Prahalad, Sampath; Rygg, Marite; Videm, Vibeke; Raychaudhuri, Soumya; Weirauch, Matthew T.; Langefeld, Carl D.; Thompson, Susan D.; Nigrovic, Peter A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-16)
      TRAF1/C5 was among the first loci shown to confer risk for inflammatory arthritis in the absence of an associated coding variant, but its genetic mechanism remains undefined. Using Immunochip data from 3,939 patients with juvenile idiopathic arthritis (JIA) and 14,412 control individuals, we identified 132 plausible common non-coding variants, reduced serially by single-nucleotide polymorphism ...
    • Identification of Endothelial Proteins in Plasma Associated With Cardiovascular Risk Factors 

      Butler, Lynn; Iglesias, Maria J.; Kruse, Larissa D.; Sanchez-Rivera, Laura; Enge, Linnea; Dusart, Philip; Hong, Mun-Gwan; Uhlén, Mathias; Renné, Thomas; Schwenk, Jochen M.; Bergstrom, Göran; Odeberg, Jacob (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-28)
      <b>Objective:</b> Endothelial cell (EC) dysfunction is a well-established response to cardiovascular disease risk factors, such as smoking and obesity. Risk factor exposure can modify EC signaling and behavior, leading to arterial and venous disease development. Here, we aimed to identify biomarker panels for the assessment of EC dysfunction, which could be useful for risk stratification or to monitor ...
    • Identification of surface proteins in a clinical Staphylococcus haemolyticus isolate by bacterial surface shaving 

      Wolden, Runa; Pain, Maria; Karlsson, Roger; Karlsson, Anders; Fredheim, Elizabeth G. Aarag; Cavanagh, Jorunn Pauline (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-07)
      <p><i>Background - </i>The skin commensal <i>Staphylococcus haemolyticus</i> is an emerging nosocomial pathogen. Despite its clinical relevance, published information about <i>S. haemolyticus</i> virulence factors is scarce. In this study, the adhesive and biofilm forming properties of ten clinical and ten commensal <i>S. haemolyticus</i> strains were examined using standard adhesion and biofilm ...
    • Identifying anti-TNF response biomarkers in ulcerative colitis using a diffusion-based signalling model 

      Singh, Amrinder; Anderssen, Endre; Fenton, Christopher Graham; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-18)
      <p><i>Motivation:</i> Resistance to anti-TNF therapy in subgroups of ulcerative colitis (UC) patients is a major challenge and incurs significant treatment costs. Identification of patients at risk of nonresponse to anti-TNF is of major clinical importance. To date, no quantitative computational framework exists to develop a complex biomarker for the prognosis of UC treatment. Modelling patient-wise ...
    • Identifying Measures Used for Assessing Quality of YouTube Videos with Patient Health Information: A Review of Current Literature 

      Gabarron, Elia; Fernandez-Luque, Luis; Armayones, Manuel; Lau, Annie YS (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Recent publications on YouTube have advocated its potential for patient education. However, a reliable description of what could be considered quality information for patient education on YouTube is missing. Objective: To identify topics associated with the concept of quality information for patient education on YouTube in the scientific literature. Methods: A literature review was ...