Viser treff 489-508 av 726

    • Pacemaker implantation in small hospitals : complication rates comparable to larger centres 

      Haug, Bjørn; Kjelsberg, Kjærsti; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Some countries have a demography that makes it necessary to maintain relatively small pacemaker centres. We wanted to assess the quality of pacemaker surgery in two such hospitals. Through patient records we gathered information on ∼535 consecutive primary pacemaker implantations in two small pacemaker centres with 30 and 80 annual operations, respectively. All patients were followed for 3 years. ...
    • PAI-1 and t-PA/PAI-1 complex potential markers of fibrinolytic bleeding after cardiac surgery employing cardiopulmonary bypass. 

      Ozolina, A.; Strike, E.; Jaunalksne, I.; Krumina, A.; Bjertnæs, Lars J.; Vanags, I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Enhanced bleeding remains a serious problem after cardiac surgery, and fibrinolysis is often involved. We speculate that lower plasma concentrations of plasminogen activator inhibitor – 1 (PAI-1) preoperatively and tissue plasminogen activator/PAI-1 (t-PA/PAI-1) complex postoperatively might predispose for enhanced fibrinolysis and increased postoperative bleeding. Totally 88 adult patients (mean ...
    • Pain and pressure pain thresholds in adolescents With chronic fatigue syndrome and healthy Controls: a cross-sectional study 

      Winger, Anette; Kvarstein, Gunnvald; Wyller, Vegard Bruun; Sulheim, Dag; Fagermoen, Frode Even; Småstuen, Milada Cvancarova; Helseth, Sølvi (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-10-06)
      Objectives<br> Although pain is a significant symptom in chronic fatigue syndrome (CFS), pain is poorly understood in adolescents with CFS. The aim of this study was to explore pain distribution and prevalence, pain intensity and its functional interference in everyday life, as well as pressure pain thresholds (PPT) in adolescents with CFS and compare this with a control group of healthy adolescents ...
    • Pain tolerance in persons with recognized and unrecognized myocardial infarction: a population-based, cross-sectional study 

      Øhrn, Andrea Sofie Henriette Milde; Nielsen, Christopher Sivert; Schirmer, Henrik; Stubhaug, Audun; Wilsgaard, Tom; Lindekleiv, Haakon (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-21)
      <b>Background</b> Unrecognized myocardial infarction (MI) is a prevalent condition associated with a similar risk of death as recognized MI. It is unknown why some persons experience MI with few or no symptoms; however, one possible explanation is attenuated pain sensitivity. To our knowledge, no previous study has examined the association between pain sensitivity and recognition of MI. <b>Methods ...
    • Palliative radiotherapy with or without additional care by a multidisciplinary palliative care team in patients with newly diagnosed cancer: A retrospective matched pairs comparison 

      Nieder, Carsten; Dalhaug, Astrid; Pawinski, Adam; Haukland, Ellinor; Mannsåker, Bård; Engljähringer, Kirsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-07)
      Purpose: To analyze survival after early palliative radiotherapy (RT) in patients managed exclusively by regular oncology staff or a multidisciplinary palliative care team (MPCT) in addition. <p>Methods: Retrospective matched pairs analysis. Comparison of two groups of 29 patients each: MPCT versus none. Early RT started within three months after cancer diagnosis. <p>Results: Bone and brain ...
    • Palliative Radiotherapy with or without Additional Care by a Multidisciplinary Palliative Care Team: A Retrospective Comparison 

      Nieder, Carsten; Angelo, Kent; Dalhaug, Astrid; Pawinski, Adam; Aandahl, Gro; Haukland, Ellinor; Engljähringer, Kirsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • A parameter for IL-10 and TGF-β mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers 

      Lind, Andreas; Brekke, Kristin; Pettersen, Frank Olav; Mollnes, Tom Eirik; Trøseid, Marius; Kvale, Dag (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men : a cross-sectional study 

      Hjelmesæth, Jøran; Hofsø, Dag; Aasheim, Erlend T.; Jenssen, Trond Geir; Moan, Johan; Hager, Helle; Røislien, Jo; Bollerslev, Jens (Journal article; Tidsskriftartikkel; Peer reviewed, 2009-02-03)
      Background: The prevalence of vitamin D insufficiency and secondary hyperparathyroidism is high among morbidly obese subjects. Further, low serum levels of 25-hydroxyvitamin D (25 [OH]D) and magnesium have been associated with increased risk of the metabolic syndrome (MS), and recently, a possible link between PTH and MS has been reported. Although it is well known that the synthesis and secretion ...
    • Pasientsikkerhet i sykehus – kunnskap eller kampanje? 

      Krogstad, Unni; Gilbert, Mads; Ormstad, Sari Susanna; Rygh, Liv; Arntzen, Elisabeth; Baalsrud, Anders; Nilsen, Stein Tore (Research report; Forskningsrapport, 2007)
      Helse Øst RHF har bedt Kunnskapssenteret om å vurdere dokumentasjonen for de seks satsingsområdene kampanjen fokuserer på: Etablere 'Rapid response team' (ekspertgruppe som tilkalles ved forverret tilstand hos pasienter) gjennomføre evidensbaserte behandlingstiltak for alle hjerteinfarktpasienter, forebygge legemiddelrelaterte pasientskader, forebygge postoperative sårinfeksjoner, forebygge ...
    • Pasientvolum og behandlingskvalitet ved hjerte- og karsykdommer 

      Norderhaug, Inger Natvig; Ingebrigsten, Tor; Krogstad, Unni; Søreide, Odd; Myhre, Hans Olav; Wiseth, Rune (Research report; Forskningsrapport, 2007)
      Kunnskapssenteret har gjennomgått og sammenstilt forskningen om pasientvolum og behandlingskvalitet med grunnlag i litteratur for perioden 2001–2006. Denne delrapporten tar for seg behandling av hjerte- og karsykdommer.The influence of hospital or physician volume on qality of health care
    • Patient satisfaction with conventional, complementary, and alternative treatment for cluster headache in a Norwegian cohort 

      Bekkelund, Svein Ivar; Ofte, Hilde Karen; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis 

      Hestad, Knut A.; Engedal, Knut; Whist, Jon Elling; Aukrust, Pål; Farup, Per Grønaas; Mollnes, Tom Eirik; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-13)
      INTRODUCTION: Several reports indicate that inflammation may play a role in depression and demonstrate enhanced systemic levels of inflammatory mediators. We hypothesized that 44 patients with a diagnosis of depression would present with a specific and different serum and cerebrospinal fluid (CSF) cytokine profile compared to 21 patients with diffuse neurological symptoms, of whom 15 had fatigue as ...
    • Peak longitudinal strain most accurately reflects myocardial segmental viability following acute myocardial infarction - an experimental study in open-chest pigs 

      Aarsæther, Erling Johan; Røsner, Assami; Straumbotn, Espen; Busund, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The extension and the transmurality of the myocardial infarction are of high predictive value for clinical outcome. The aim of the study was to characterize the ability of longitudinal, circumferential and radial strain measured by 2-dimensional speckle tracking echocardiography (2D-STE) to predict the extent of necrosis in myocardial segments following acute myocardial infarction and to separate ...
    • The Pedicled LICAP Flap Combined with a Free Abdominal Flap In Autologous Breast Reconstructions 

      Sjøberg, Thomas K.; Weerd, Louis de (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-01)
      Background: <br>Previous surgery or slim body configuration can limit the size of the available abdominal flap in autologous breast reconstruction. However, redundant skin and subcutaneous tissue lateral to the mastectomy site can be utilized as the pedicled lateral intercostal artery perforator (LICAP) flap. This study evaluates the combination of a free abdominal flap and a pedicled LICAP ...
    • Pembrolizumab as second-line therapy in non-small cell lung cancer in northern Norway: budget impact and expected gain—a model-based analysis 

      Norum, Jan; Antonsen, Margaret Aarag; Tollåli, Geir; Al-Shibli, Khalid; Andersen, Gry; Svanqvist, Kristin-Helene; Helbekkmo, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-29)
      1 Norum J, et al . ESMO Open 2017; 2 :e000222. doi:10.1136/esmoopen-2017-000222 Open Access Abstr A ct Background P embrolizumab is a new drug approved in several countries for second-line therapy in non-small cell lung cancer (NSCLC) being programmed cell death ligand (PD-L1) positive. This drug has a high cost, and the cost- effectiveness ratio has been debated. Patients ...
    • Perforator-guided drug injection at the point of nerve entrapment 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-14)
      Letter to the Editor
    • Perforator-guided drug injection in the treatment of abdominal wall pain 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-25)
      Background. Pain from the abdominal wall can be caused by nerve entrapment, a condition called abdominal cutaneous nerve entrapment syndrome (ACNES). As an alternative to surgery, ACNES may be treated with injection of local anesthetics, corticosteroids, or botulinum toxin at the point of maximal pain. Method. The point of maximal pain was marked on the abdominal skin. Using color Doppler ultrasound, ...
    • Performance of Norwegian civilian EMTs and army medics in penetrating trauma: a controlled simulation-based assessment 

      Blix, Sigurd Wisborg; Melau, Jørgen; Lund-Kordahl, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-25)
      <p><i>Background</i>: Penetrating trauma kills rapidly. Thorough and efficient examination and aggressive hemorrhage control is important to save lives. The aim of this study was to assess the skills of civilian Emergency Medical Technicians (EMTs) in bleeding examination and control compared to Army Medics. Our hypothesis was that civilian pre‐hospital systems perform at a lower level compared to ...
    • PET-CT in the-subarctic region of Norway 2010-2013. At the edge of what is possible? 

      Norum, Jan; Søndergaard, Ursula; Traasdahl, Erik; Nieder, Carsten; Tollåli, Geir; Andersen, Gry; Sundset, Rune (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-28)
      Background It is challenging to obtain a similar access to positron emission tomography/computed tomography (PET-CT) within the whole region served. In the subarctic and arctic region of Norway, significant distances, weather conditions and seasonable darkness have been challenging when the health care provider has aimed for a high quality PET-CT service with similar availability to all inhabitants. ...
    • The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction and body height. The Tromsø Study 

      Jorde, Rolf; Schirmer, Henrik; Wilsgaard, Tom; Joakimsen, Ragnar Martin; Mathiesen, Ellisiv B.; Njølstad, Inger; Løchen, Maja-Lisa; Figenschau, Yngve Anton; Svartberg, Johan; Hutchinson, Moira Strand; Kjærgaard, Marie; Jørgensen, Lone; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objective: High serum thyrotropin (TSH) levels predict cardiovascular disease (CVD). Recently several single nucleotide polymorphisms (SNPs) associated with TSH levels have been identified, one of them being the rs4704397 SNP in the phosphodiesterase 8B (PDE8B) gene. If the relation between thyroid function and CVD is causal, one could also expect rs4704397 genotypes to predict CVD and possibly ...