Viser treff 762-781 av 794

    • Validation of the graded prognostic assessment for lung cancer with brain metastases using molecular markers(lung-molGPA) 

      Nieder, Carsten; Hintz, Mandy; Oehlke, Oliver; Bilger, Angelika; Grosu, Anca L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-26)
      Background:<br>Many patients with brain metastases from non-small cell lung cancer have limited survival, while others survive for several years, depending on patterns of spread, EGFR and ALK alterations, among others. The purpose of this study was to validate a new prognostic model (Lung-molGPA) originally derived from a North American database.<br>Patients and methods:<br>This retrospective study ...
    • Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study 

      Huijben, Jilske A.; Volovici, Victor; Cnossen, Maryse C.; Haitsma, Iain K.; Stocchetti, Nino; Maas, Andrew I. R.; Menon, David K.; Ercole, Ari; Citerio, Giuseppe; Nelson, David; Polinder, Suzanne; Steyerberg, Ewout W.; Lingsma, Hester F.; van der Jagt, Mathieu; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-13)
      <p><i>Background</i>: General supportive and preventive measures in the intensive care management of traumatic brain injury (TBI) aim to prevent or limit secondary brain injury and optimize recovery. The aim of this survey was to assess and quantify variation in perceptions on intensive care unit (ICU) management of patients with TBI in European neurotrauma centers.</p> <p><i>Methods</i>: We ...
    • Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study 

      Van Essen, Thomas; den Boogert, HF; Cnossen, MC; De Ruiter, Godard CW; Haitsma, Ian; Polinder, S; Steyerberg, Ewout W.; Menon, David; Maas, Andrew I. R.; Lingsma, Hester F; Peul, Wilco; Andelic, Nada; Helseth, Eirik; Roise, O; Røe, Cecilie; Vik, Anne; Skandsen, Toril; Anke, Audny; Frisvold, Shirin Kordasti (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-19)
      <p><i>Background</i>: Neurosurgical management of traumatic brain injury (TBI) is challenging, with only low-quality evidence. We aimed to explore differences in neurosurgical strategies for TBI across Europe.</p> <p><i>Methods</i>: A survey was sent to 68 centers participating in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. The ...
    • Variations in contact patterns and dispatch guideline adherence between Norwegian emergency medical communication centres - a cross-sectional study 

      Ellensen, Eirin Nybø; Hunskaar, Steinar; Wisborg, Torben; Zakariassen, Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Vasopressin impairs brain, heart and kidney perfusion: an experimental study in pigs after transient myocardial ischemia 

      Müller, Stig; How, Ole-Jakob; Hermansen, Stig Eggen; Stenberg, Thor Allan; Sager, Georg; Myrmel, Truls (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-02-21)
      Introduction: Arginine vasopressin (AVP) is increasingly used to restore mean arterial pressure (MAP) in low-pressure shock states unresponsive to conventional inotropes. This is potentially deleterious since AVP is also known to reduce cardiac output by increasing vascular resistance. The effects of AVP on blood flow to vital organs and cardiac performance in a circulation altered by cardiac ...
    • Venous thromboembolism increases the risk of atrial fibrillation: The tromsø study 

      Hald, Erin Mathiesen; Enga, Kristin Fjeldstad; Løchen, Maja-Lisa; Mathiesen, Ellisiv B.; Njølstad, Inger; Wilsgaard, Tom; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Vessel co-option in primary human tumors and metastases: an obstacle to effective anti-angiogenic treatment? 

      Dønnem, Tom; Hu, Jiangting; Ferguson, M.; Adighibe, Omanma; Snell, Cameron; Harris, Adrian L.; Gatter, Kevin C; Pezzella, F (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Angiogenesis has been regarded as essential for tumor growth and progression. Studies of many human tumors, however, suggest that their microcirculation may be provided by nonsprouting vessels and that a variety of tumors can grow and metastasize without angiogenesis. Vessel co-option, where tumor cells migrate along the preexisting vessels of the host organ, is regarded as an alternative tumor ...
    • Video conferencing versus telephone calls for team work across hospitals : a qualitative study on simulated emergencies 

      Bolle, Stein Roald; Gilbert, Mads; Larsen, Frank Atle; Hagen, Oddvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2009)
    • Violence and child mental health in Brazil: The Itaboraí Youth Study methods and findings 

      Bordin, Isabel AS; Duarte, Cristiane S.; Ribeiro, W.S.; Paula, C.S.; Coutinho, Evandro Silva Freire; Sourander, A; Rønning, John Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-17)
      <p><i>Objectives</i>: To demonstrate a study design that could be useful in low‐resource and violent urban settings and to estimate the prevalence of child violence exposure (at home, community, and school) and child mental health problems in a low‐income medium‐size city.</p> <p><i>Methods</i>: The Itaboraí Youth Study is a Norway–Brazil collaborative longitudinal study conducted in Itaboraí ...
    • Visceral fat is strongly associated with post-transplant diabetes mellitus and glucose metabolism 1 year after kidney transplantation 

      Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Åsberg, Anders; Godang, Kristin; Hartmann, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-16)
      Body composition after kidney transplantation is linked to glucose metabolism, and impaired glucose metabolism is associated with increased risk of cardiovascular events and death. One year after transplantation we examined 150 patients for new-onset diabetes performing OGTTs and body composition measurements including visceral adipose tissue (VAT) content from dual-energy X-ray absorptiometry ...
    • Vitamin D and cognitive function: A Mendelian randomisation study 

      Maddock, Jane; Zhou, Ang; Cavadino, Alana; Kuźma, Elżbieta; Bao, Yanchun; Smart, Melissa C.; Saum, Kai-Uwe; Schöttker, Ben; Engmann, Jorgen; Kjærgaard, Marie; Karhunen, Ville; Zhan, Yiqiang; Lehtimäki, Terho; Rovio, Suvi P.; Byberg, Liisa; Lahti, Jari; Marques-Vidal, Pedro; Sen, Abhijit; Perna, Laura; Schirmer, Henrik; Singh-Manoux, Archana; Auvinen, Juha; Hutri-Kähönen, Nina; Kähönen, Mika; Kilander, Lena; Räikkönen, Katri; Melhus, Håkan; Ingelsson, Erik; Guessous, Idris; Petrovic, Katja E.; Schmidt, Helena; Schmidt, Reinhold; Vollenweider, Peter; Lind, Lars; Eriksson, Johan G.; Michaëlsson, Karl; Raitakari, Olli T; Hägg, Sara; Pedersen, Nancy L.; Herzig, Karl-Heinz; Järvelin, Marjo-Riitta; Veijola, Juha; Kivimäki, Mika; Jorde, Rolf; Brenner, Hermann; Kumari, Meena; Power, Chris; Llewellyn, David J.; Hyppönen, Elina (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-16)
      The causal nature of the association between hypovitaminosis D and poor cognitive function in mid- to later-life is uncertain. Using a Mendelian randomisation(MR) approach, we examined the causal relationship between 25(OH)D and cognitive function. Data came from 172,349 participants from 17 cohorts. DHCR7(rs12785878), CYP2R1 rs12794714) and their combined synthesis score were chosen to proxy 25(OH)D. ...
    • Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium 

      Gaksch, Martin; Jorde, Rolf; Grimnes, Guri; Joakimsen, Ragnar Martin; Schirmer, Henrik; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Njølstad, Inger; Løchen, Maja-Lisa; März, Winfried; Kleber, Marcus E.; Tomaschitz, Andreas; Grübler, Martin; Eiriksdottir, Gudny; Gudmundsson, Elias F.; Harris, Tamara B.; Cotch, Mary Frances; Aspelund, Thor; Gudnason, Vilmundur; Rutters, Femke; Beulens, Joline W.J.; Van't Riet, Esther; Nijpels, Giel; Dekker, Jacqueline M.; Grove-Laugesen, Diana; Rejnmark, Lars; Busch, Markus A.; Mensink, Gert B.M.; Scheidt-Nave, Christa; Thamm, Michael; Swart, Karin M.A.; Brouwer, Ingeborg A.; Lips, Paul; Van Schoor, Natasja M.; Sempos, Christopher T.; Durazo-Arvizu, Ramón A.; Škrabáková, Zuzana; Dowling, Kirsten G.; Cashman, Kevin D.; Kiely, Mairead; Pilz, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-16)
      Background:<br>Vitamin D deficiency may be a risk factor for mortality but previous meta-analyses lacked standardization of laboratory methods for 25-hydroxyvitamin D (25[OH]D) concentrations and used aggregate data instead of individual participant data (IPD). We therefore performed an IPD meta-analysis on the association between standardized serum 25(OH)D and mortality.<br>Methods:<br>In a European ...
    • Vitamin D deficiency in Europe: pandemic? 

      Cashman, Kevin D.; Dowling, Kirsten G.; Škrabáková, Zuzana; Gonzalez-Gross, Marcela; Valtueña, Jara; De Henauw, Stefaan; Moreno, Luis; Damsgaard, Camilla T.; Michaelsen, Kim F.; Mølgaard, Christian; Jorde, Rolf; Grimnes, Guri; Moschonis, George; Mavrogianni, Christina; Manios, Yannis; Thamm, Michael; Mensink, Gert B.M.; Rabenberg, Martina; Busch, Markus A.; Cox, Lorna; Meadows, Sarah; Goldberg, Gail; Prentice, Ann; Dekker, Jacqueline M.; Nijpels, Giel; Pilz, Stefan; Swart, Karin M.; Van Schoor, Natasja M.; Lips, Paul; Eiriksdóttir, Gudny; Gudnason, Vilmundur; Cotch, Mary Frances; Koskinen, Seppo; Lamberg-Allardt, Christel; Durazo-Arvizu, Ramon A.; Sempos, Christopher T.; Kiely, Mairead (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-10)
      Background:<br>Vitamin D deficiency has been described as being pandemic, but serum 25-hydroxyvitamin D [25(OH)D] distribution data for the European Union are of very variable quality. The NIH-led international Vitamin D Standardization Program (VDSP) has developed protocols for standardizing existing 25(OH)D values from national health/nutrition surveys.<br>Objective:<br>This study applied VDSP ...
    • Vitamin D deficiency is common in psychogeriatric patients, independent of diagnosis 

      Grønli, Ole Kristian; Kvamme, Jan-Magnus; Jorde, Rolf; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-05-08)
      Background:Previous studies have found an association between psychiatric disorders and vitamin D deficiency, but most studies have focused on depression. This study aimed to establish the prevalence of vitamin D deficiency in elderly patients with a wider range of psychiatric diagnoses. Method: The study included elderly patients (>64 years) referred to a psychiatric hospital in Northern Norway ...
    • Vitamin D supplementation does not improve CVD risk factors in vitamin D-insufficient subjects 

      Kubiak, Julia Magdalena; Thorsby, Per Medbøe; Kamycheva, Elena; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06)
      <p><i>Objective</i>: Low serum 25(OH)D levels are associated with cardiovascular disease (CVD) and some of its risk factors. However, in interventional studies, the effects of vitamin D supplementation have been uncertain, possibly due to inclusion of vitamin D-sufficient subjects. Our aim was therefore to examine effects of vitamin D supplementation on CVD risk factors in vitamin D-insufficient ...
    • Vitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarction. 

      Næsgaard, Patrycja; Grundt, Heidi; Nordøy, Arne; Staines, Harry; Nilsen, Dennis W.T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-24)
      Background: <br> Fish is the natural dietary source of vitamin D. Reports on the influence of purified omega-3 fatty acids on its uptake are scarce. <br> Objectives: <br> We investigated the impact of a purified high-dose omega-3 compound compared to corn oil on 25-hydroxyvitamin D [25(OH)D] levels following an acute myocardial infarction. <br> Methods: <br> 228 patients were randomized 1:1 to receive ...
    • A web-based telemedicine system for low-resource settings 13 years on: insights from referrers and specialists 

      Patterson, Victor; Wootton, Richard (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: One way to tackle health inequalities in resource-poor settings is to establish links between doctors and health professionals there and specialists elsewhere using web-based telemedicine. One such system run by the Swinfen Charitable Trust has been in existence for 13 years which is an unusually long time for such systems. Objective: We wanted to gain some insights into whether and ...
    • Weight Change and Risk of Venous Thromboembolism: The Tromsø Study 

      Horvei, Lars Daae; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-20)
      <b>Background:</b> Obesity is a major risk factor for venous thromboembolism (VTE), but it is unknown to what extent weight change over time affects VTE risk.<br> <b>Aims:</b> To investigate the association between weight change and risk of incident VTE in a population-based cohort with repeated measurements.<br> <b>Methods:</b> Participant data were collected from the Tromsø 3 (1986–87), 4 ...
    • Welfare and labour-force participation of kinship foster mothers 

      Holtan, Amy; Thørnblad, Renee (Journal article; Tidsskriftartikkel, 2009)
      Objective: Kinship foster care has become the placement of choice in the Western world. This article explores the welfare, labour-force participation, and caregiving role of kinship foster mothers in Norway. <br>Method: The study supplements a quantitative study of Norwegian long-term kinship and nonkinship foster care with a qualitative study of parenting in formal kinship foster care. A total of ...
    • What are diabetes patients discussing on social media? 

      Gabarron, Elia; Bradway, Meghan; Årsand, Eirik (Conference object; Konferansebidrag, 2016-11-15)
      Social media channels are being used more and more by people with diabetes for exchanging health information, experiences with their chronic condition, and asking and giving advice to their peers[1]. The objective of this study is to describe the nature of the information that is shared on Norwegian diabetes social media groups, and the users’ reactions to these posts.