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Marine Mammal Brucella Reference Strains Are Attenuated in a BALB/c Mouse Model
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-09)
Brucellosis is a zoonosis of worldwide distribution with numerous animal host species. Since the novel isolation of Brucella spp. from marine mammals in 1994 the bacteria have been isolated from various marine mammal hosts. The marine mammal reference strains Brucella pinnipedialis 12890 (harbour seal, Phoca vitulina) and Brucella ceti 12891 (harbour porpoise, Phocoena phocoena) were included in ...
Brucella pinnipedialis in hooded seal (Cystophora cristata) primary epithelial cells
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-25)
Background: Marine Brucella spp. have been isolated from numerous pinniped and cetacean species, but pathological
findings in association with infection with Brucella pinnipedialis in pinnipeds have been sparse. The capacity
of brucellae to survive and replicate within host macrophages underlies their important ability to produce chronic
infections, but previous work has shown that B. pinnipedialis ...
Experimental challenge of atlantic cod (Gadus morhua) with a brucella pinnipedialis strain from hooded seal (Cystophora cristata)
(Peer reviewed; Journal article; Tidsskriftsartikkel, 2016-07-14)
Pathology has not been observed in true seals infected with Brucella pinnipedialis. A lack of intracellular survival and multiplication of B. pinnipedialis in hooded seal (Cystophora cristata) macrophages in vitro indicates a lack of chronic infection in hooded seals. Both epidemiology and bacteriological patterns in the hooded seal point to a transient infection of environmental origin, possibly ...