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Bacterial flagellin : a novel adjuvant for vaccine strategies
(Doctoral thesis; Doktorgradsavhandling, 2011-10-18)
Flagellin is the principal structural protein in the locomotive organ flagellum present on flagellated bacteria, and is known to be an important evolutionarily conserved PAMP. Flagellin has been shown to bind to the PRR TLR5 which induces innate immune system responses and signaling pathways. In mammals, much focus has been placed on this protein in vaccine studies for its possible function as an ...