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Studies of JAK/STAT signaling in Atlantic salmon
(Doctoral thesis; Doktorgradsavhandling, 2014-06-27)
In mammals the JAK-STAT pathway plays a significant role in mediating the biological activities of both type I and type II IFN, where JAKs are receptor associated kinases and STATs the transcription factors they activate. At the start of this project the knowledge of the JAK-STAT pathway in fish in general was scarce and there were few reports describing the function of any JAK-STAT family member ...