• Intracellular distribution and transcriptional regulation of Atlantic salmon (Salmo salar) Rab5c, 7a and 27a homologs by immune stimuli 

      Nepal, Arpita; Wolfson, Deanna; Ahluwalia, Balpreet Singh; Jensen, Ingvill; Jørgensen, Jorunn B; Iliev, Dimitar Borisov (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-31)
      Rab GTPases control trafficking of intracellular vesicles and are key regulators of endocytic and secretory pathways. Due to their specific distribution, they may serve as markers for different endolysosomal compartments. Since Rab GTPases are involved in uptake and trafficking of endocytosed ligands and cell receptors, as well as secretion of immune mediators, they have been implicated in diverse ...
    • Stimulation of exosome release by extracellular DNA is conserved across multiple cell types 

      Iliev, Dimitar Borisov; Strandskog, Guro; Nepal, Arpita; Aspar, Augusta; Olsen, Randi; Jørgensen, Jorunn B; Wolfson, Deanna; Ahluwalia, Balpreet Singh; Handzhiyski, Jordan; Mironova, Roumyana (Journal article; Tidsskriftartikkel; Manuskript; Peer reviewed; Preprint, 2018-06-28)
      Exosomes are distinguished from other types of extracellular vesicles by their small and relatively uniform size (30-100 nm) and their composition which reflects their endo-lysosomal origin. Involvement of these extracellular organelles in intercellular communication and their implication in pathological conditions has fuelled intensive research on mammalian exosomes; however, currently, very little ...