Background - Colorectal liver metastasis (CLM) is a leading cause of colorectal cancer mortality, and the response to immune checkpoint inhibition (ICI) in microsatellite-stable CRC has been disappointing. Administration of cytotoxic chemotherapy may cause increased density of tumor-infiltrating T cells, which has been associated with improved response to ICI. This study aimed to quantify and ...

Lectotypes are designated for the predaceous midges, <i>Ceratopogon circumdatus</i> Stæger, 1839, and <i<Ceratopogon binotatus</i> Stæger, 1839 housed in the Copenhagen Zoological Museum, Denmark, and both species are redescribed and photographed. <i>Ceratopogon circumdatus</i> is removed from synonymy with <i>Bezzia solstitialis</i> (Winnertz, 1852) and recognized as a new synonym of <i>Bezzia ...

There is still limited consensus on the evolutionary history of species-rich temperate alpine floras due to a lack of comparable and high-quality phylogenetic data covering multiple plant lineages. Here we reconstructed when and how European alpine plant lineages diversified, i.e., the tempo and drivers of speciation events. We performed full-plastome phylogenomics and used multi-clade comparative ...

Predicting the impact of global climate change on the biosphere has become one of the most important efforts in ecology. Ecosystems worldwide are changing rapidly as a consequence of global warming, yet our understanding of the consequences of these changes on populations is limited. The North Atlantic Oscillation (NAO) has been used as a proxy for “climate” in several ecological studies, but this ...

The North Atlantic islands of the Faroe Islands, Iceland and Greenland have always been relatively poor in terms of native timber resources, due to their cold climate and exposed topography. Nevertheless, timber was vital to the material culture of the Norse settlers of these islands, and driftwood often met this need. As in subarctic Norway, where trees are also scarce, driftwood use and ownership ...

Det samiske senteret Várdobáiki sámi guovddáš har i jubileet «Nasjonaljubileet 2030 – Norge i tusen år» som mål å fremme kunnskap om samenes rolle og posisjon i middelalderen. I denne artikkelen presenterer jeg hvordan de gjennom prosjektet «Tore Hunds čehporis» og ved aktivering av duodji (samisk håndverkstradisjon) åpner for nye blikk på nasjonale fortellinger. Jeg diskuterer hvordan «Tore Hunds ...

In 2010, the first shaman festival to be held in the Nordic countries opened its doors to the public in the county of Lavangen, Northern Norway (Fig. 1). The festival is named Isogaisa and presented as an indigenous festival highlighting the spiritual traditions of indigenous people. At this annual festival, shamans from all over the world gather to perform ceremonies and exchange knowledge.

The red-listed, amphi-Atlantic sedge Carex rufina is highly specialized to certain alpine snowbeds, and threatened by current changes in snow cover duration and moisture conditions. Here we address its range-wide genetic diversity, history, and conservation using amplified fragment length polymorphisms (AFLPs). Despite extensive primer testing, we detected very low overall diversity (4.1% polymorphic ...

Species breeding at high latitudes face a significant challenge of surviving the winter. Such conditions are particularly severe for diurnal marine endotherms such as seabirds. A critical question is therefore what behavioural strategies such species adopt to maximise survival probability. We tested 3 hypotheses: (1) they migrate to lower latitudes to exploit longer day length (‘sun-chasing’), (2) ...

Utgravningene av totalt elleve lokaliteter på Skarpeneset i 2008, med et begrenset tillegg i 2009, avdekket overraskende fire store, rektangulære tufter, mer eller mindre nedgravde i bakken, på to av lokalitetene. Tuftene er datert samlet til 7000 – 6500/6400 f.Kr. Det foreslås at de er rester etter hus med parvis skråstilte, takbærende stolper, uten markerte ildsteder og med minst to åpninger/innganger. ...