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dc.contributor.authorBakken, Toril
dc.contributor.authorBraaten, Tonje
dc.contributor.authorOlsen, Anja
dc.contributor.authorKyrø, Cecilie
dc.contributor.authorLund, Eiliv
dc.contributor.authorSkeie, Guri
dc.date.accessioned2017-03-08T15:15:44Z
dc.date.available2017-03-08T15:15:44Z
dc.date.issued2016-01-13
dc.description.abstractThere is evidence that consumption of foods containing dietary fiber decreases the risk of colorectal cancer (CRC). Whole grains contain dietary fiber, as well as a range of micronutrients and bioactive compounds, but the association between the consumption of whole grains and the risk of CRC remains less studied. The aim of the present study was to investigate the association between whole-grain bread consumption and CRC incidence among Norwegian women, using data from a prospective cohort study (the Norwegian Women and Cancer Study). Dietary intake was estimated from the food-frequency questionnaires of 78,254 women in the cohort (median age: 55 years), and these women were then followed up for CRC incidence. During the 9 years of median follow-up, 795 women were diagnosed with CRC (316 proximal, 193 distal, 218 rectal). Associations between whole-grain bread consumption and the risk of CRC (including colorectal subsites) were investigated using Cox proportional hazards regression models. When compared to the low consumption group, the hazard ratio for CRC was 0.89 (95% confidence interval (CI): 0.72–1.09) for the high consumption group and 0.86 (95% CI: 0.72–1.02) for the medium consumption group in a multivariable model. Overall, no association between whole-grain bread consumption and CRC was found.en_US
dc.descriptionPublished version. Source at <a href=http://doi.org/10.3390/nu8010040>http://doi.org/10.3390/nu8010040</a>. License <a href=https://creativecommons.org/licenses/by/4.0/>CC BY 4.0</a>.en_US
dc.identifier.citationBakken T, Braaten T, Olsen A, Kyrø C, Lund e, Skeie G. Consumption of Whole-Grain Bread and Risk of Colorectal Cancer among Norwegian Women (the NOWAC Study). Nutrients. 2016;8(1)en_US
dc.identifier.cristinIDFRIDAID 1313656
dc.identifier.doi10.3390/nu8010040
dc.identifier.issn2072-6643
dc.identifier.urihttps://hdl.handle.net/10037/10487
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalNutrients
dc.rights.accessRightsopenAccessen_US
dc.subjectcolorectal canceren_US
dc.subjectproximal colonen_US
dc.subjectwhole-grainen_US
dc.subjectbreaden_US
dc.subjectcohorten_US
dc.subjectprospectiveen_US
dc.subjectwomenen_US
dc.subjectNorwayen_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 811en_US
dc.titleConsumption of Whole-Grain Bread and Risk of Colorectal Cancer among Norwegian Women (the NOWAC Study)en_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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