Blar i utgivelsesdato Prosjektoppgave forskerlinja i medisin

Viser treff 21-31 av 31

    • Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor 

      Lorentzen, Elias Myrvoll; Henriksen, Stian; Kaur, Amandeep; Kro, Grete Birkeland; Hammarström, Clara; Hirsch, Hans H; Midtvedt, Karsten; Rinaldo, Christine Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed; Mastergradsoppgave; Master thesis, 2020-01-10)
      <i>Background</i> - BK Polyomavirus (BKPyV) causes premature graft failure in 1 to 15% of kidney transplant (KT) recipients. High-level BKPyV-viruria and BKPyV-DNAemia precede polyomavirus-associated nephropathy (PyVAN), and guide clinical management decisions. In most cases, BKPyV appears to come from the donor kidney, but data from biopsy-proven PyVAN cases are lacking. Here, we report the early ...

    • Body mass index and cognitive function in community-living elderly men and women: The Tromsø Study 

      Ylvisaker, Ida J.E. (Master thesis; Mastergradsoppgave, 2020-04-01)
      <p><i>Background:</i> Previous studies have reported conflicting results regarding the relationship between cognitive function and nutritional status in the elderly. The primary objective of this study was to investigate the associations between body mass index (BMI) and cognitive function in a sample of community-living elderly men and women. <p><i>Methods:</i> This population-based study comprised ...

    • The effect of one-hour hypothermia on long term spatial memory in male Long Evans rats 

      Marsteen, Håvar (Master thesis; Mastergradsoppgave, 2020-11-01)
      The human body is willing to expend great amount of energy on mechanisms that keep the core temperature within a very small range. When these mechanisms are overwhelmed the body temperature either rises (hyperthermia) or drops (hypothermia). Hypothermia has earlier been used to induce retrograde amnesia (forgetting) and we have in this study examined if hypothermia can affect a robust long-term ...

    • Factors influencing mentors’ satisfaction: A study from medical schools in Norway and Canada 

      Skjevik, Elise Pauline; Schei, Edvin; Boudreau, J. Donald; Tjølsen, Arne; Ringberg, Unni; Fuks, Abraham; Kvernenes, Monika; Ofstad, Eirik H. (Master thesis; Mastergradsoppgave, 2020-11-01)
      <p><i>Phenomenon:</i> The mentoring of undergraduate medical students has been shown to benefit the mentors; however, detailed information on the factors that influence the satisfaction and motivation of mentors remains unclear. Such knowledge can be useful in sustaining group mentorship programs. The aim of this study was to investigate the experiences and perspectives of mentors to ascertain the ...

    • Challenges and objections to body temperature monitoring among pre-hospital personnel. A modified nominal group technique study. 

      Scott, Remi William (Mastergradsoppgave; Master thesis, 2021-11-01)
      Background: Hypothermia is common and correlates with mortality and morbidity for emergency patients, but a pre-hospital temperature measurement is often omitted. Objectives: To investigate barriers that pre-hospital care (PHC) providers experience with temperature monitoring, and solutions to the problem. Study design: Modified nominal group technique. Materials and methods: Fourteen PHC providers ...

    • Trends in prevalence of ultrasound-assessed carotid atherosclerosis in a general population over time. The Tromsø Study 1994-2016 

      Wang-Iversen, Rosa Elisabeth Theresia; Eltoft, Agnethe; Johnsen, Stein Harald; Mathiesen, Ellisiv B. (Master thesis; Mastergradsoppgave, 2021-11-11)
      <p><i>Background:</i> During the past decades, there has been a shift in risk factor levels in many high-income countries, with decrease in smoking, blood pressure and cholesterol levels, while body mass index, obesity and diabetes increase. The diverging trends may have opposite effects on prevalence of atherosclerosis. We aimed to assess carotid plaque prevalence and the association with risk ...

    • Recombinant T-cell receptors from HPA-1a specific T-cells 

      Sætre, Thomas (Mastergradsoppgave; Master thesis, 2022-02-01)
      Fetal- and neonatal alloimmune thrombocytopenia is a condition that can cause hemorrhage and potential brain damage or death in neonates. It is most often a result of maternal alloantibodies specific for fetal Human Platelet antigen 1a (HPA-1a) that destroy fetal platelets. The recognition of the HPA-1a peptide-MHC complex by T-cells involve a peculiar form of T-cell receptor peptide-MHC ...

    • Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer — A Multi-Institutional Study 

      Stoen, Maria J.; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona I.; Ingebriktsen, Lise M.; Donnem, Tom; Lombardi, Ana P. G.; Kilvaer, Thomas K.; Busund, Lill-Tove R.; Richardsen, Elin (Master thesis; Mastergradsoppgave; Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      <p><i>Background:</i> MicroRNAs (miRs) have critical regulatory roles in cell functions, and are involved in prostate cancer tumorigenesis. miR-20a-5p is a member of the oncogenic miR-17-92 cluster. Overexpressed miR-20a-5p has been shown to increase both cell proliferation and cell migration in cancers. The aim of our cohort study was to evaluate the prognostic role of miR-20a-5p in prostate cancer. ...

    • Performance and clinical applicability of machine learning in liver computed tomography imaging: a systematic review 

      Joakimsen, Henrik Lykke (Master thesis; Mastergradsoppgave, 2023-09-12)
      Abstract Objectives: Machine learning (ML) for medical imaging is emerging for several organs and image modalities. Our objectives were to provide clinicians with an overview of this field by answering the following questions: (1) How is ML applied in liver computed tomography (CT) imaging? (2) How well do ML systems perform in liver CT imaging? (3) What are the clinical applications of ML in liver ...

    • Treatment of Cardiovascular Dysfunction With PDE5-Inhibitors – Temperature Dependent Effects on Transport and Metabolism of cAMP and cGMP 

      Selli, Anders Lund (Master thesis; Mastergradsoppgave, 2023-10-21)
      Introduction: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is reported after rewarming from below 15°C, advocating a need for evidence-based treatment guidelines. In ...

    • Outcome of aneurysmal subarachnoid hemorrhage in a population-based cohort: Retrospective registry study 

      Iversen, Mathilde Vea (Master thesis; Mastergradsoppgave, 2023-10-31)
      Background: Studies of aneurysmal subarachnoid hemorrhage (aSAH) report an association between higher patient volumes and better outcomes. In regions with dispersed settlement, this must be balanced against the advantages with shorter pre-hospital transport times and timely access. The aim of this study is to report outcome for unselected aSAH-cases from a well-defined rural population treated in a ...