Viser treff 846-865 av 930

    • Synthesis and Evaluation of the Tetracyclic Ring-System of Isocryptolepine and Regioiso-Mers for Antimalarial, Antiproliferative and Antimicrobial Activities 

      Håheim, Katja Stangeland; Lindback, Emil; Tan, Kah Ni; Albrigtsen, Marte; Helgeland, Ida Therese Urdal; Clemence, Lauga; Matringe, Theodora; Kennedy, Emily K.; Andersen, Jeanette Hammer; Avery, Vicky M.; Sydnes, Magne Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-30)
      A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities. The novel hydroiodide salts 10 and 21 showed the most promising antiplasmodial inhibition, with compound 10 displaying higher selectivity than the employed standards. The antiproliferative assay revealed novel pyridophenanthridine ...
    • Systems biology – Current status and challenges 

      Zupanic, Anze; Bernstein, Hans Christopher; Heiland, Ines (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      We put together a special issue on current approaches in systems biology with a focus on mathematical modeling of metabolic networks. Mathematical models have increasingly been used to unravel molecular mechanisms of complex dynamic biological processes. We here provide a short introduction into the topics covered in this special issue, highlighting current developments and challenges.
    • T-box transcription factor eomesodermin/Tbr2 in Atlantic cod (Gadus morhua L.): Molecular characterization, promoter structure and function analysis 

      Chi, Heng; Sørmo, Kristian Gillebo; Diao, Jing; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
      Eomesodermin (Eomes) is a member of T-box transcription factor family and plays an important role in the regulation of a wide variety of developmental processes and immune response in animals. Here we report cloning and characterization of the full-length cDNA of Atlantic cod Eomes (GmEomes), which possesses a TBOX_3 domain similar to its counterpart in mammals. The regulated expression was observed ...
    • The teleost polymeric Ig receptor counterpart in ballan wrasse (Labrus bergylta) differs from pIgR in higher vertebrates 

      Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf; Hordvik, Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-13)
      As mucosal barriers in fish are the main sites where pathogens are encountered, mucosal immunity is crucial to avoid infection in the aquatic environment. In teleost fish, immunoglobulins are present in gut, gill and skin mucus, although not in the same amounts as in higher vertebrates. In mammals, the poly-Ig receptor (pIgR) is synthesized in epithelial cells and mediates the active transport ...
    • Temperature dependent growth rate, lipid content and fatty acid composition of the marine cold-water diatom Porosira glacialis 

      Svenning, Jon Brage; Dalheim, Lars; Eilertsen, Hans Christian; Vasskog, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-27)
      In this study, the northern cold-water marine diatom <i>Porosira glacialis</i> was cultivated in a pilot-scale mass cultivation system at 5 different temperatures (−2 to 12 °C), in order to evaluate temperature-dependent growth rate (in vitro Chl <i>a</i>), lipid content (Folch's method) and fatty acid (FA) composition (GC–MS) in the exponential growth phase. We found that <i>P. glacialis</i> has a ...
    • Temperature-dependent lipid accumulation in the polar marine microalga Chlamydomonas malina RCC2488 

      Morales-Sanchez, Daniela; Schulze, Peter Simon Claus; Kiron, Viswanath; Wijffels, Rene Hubertus (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-23)
      The exploration of cold-adapted microalgae offers a wide range of biotechnological applications that can be used for human, animal, and environmental benefits in colder climates. Previously, when the polar marine microalga <i>Chlamydomonas malina</i> RCC2488 was cultivated under both nitrogen replete and depleted conditions at 8°C, it accumulated lipids and carbohydrates (up to 32 and 49%, respectively), ...
    • Temporal patterns in the soundscape of a Norwegian gateway to the Arctic 

      Aniceto, Ana Sofia; Ferguson, Elizabeth L.; Pedersen, Geir; Tarroux, Arnaud; Primicerio, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-10)
      As an Arctic gateway, the Norwegian Sea sustains a rich diversity of seasonal and resident species of soniferous animals, vulnerable to the efects of climate change and anthropogenic activities. We show the occurrence of seasonal patterns of acoustic signals in a small canyon of Northern Norway, and investigate cetacean vocal behavior, human-made noise, and climatic contributions to underwater ...
    • Terra nullius, Inuit Habitation and Norse Occupation with Special Emphasis on the 1933 East Greenland Case 

      Ørebech, Peter Thomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05)
      Sovereignty acquired by occupation entails “recognize[d] title based on discovery,” “a reasonable period [of] … effective occupation of the region claimed to be discovered” and “the continuous and peaceful display of State authority.” Only terra nullius is subject to occupation. A territory inhabited by indigenous groups that sustain social and political organization may impede an occupying power ...
    • Testing a size sorting grid in the brown shrimp (Crangon Crangon Linnaeus, 1758) beam trawl fishery 

      Veiga-Malta, Tiago; Feekings, J.P.; Frandsen, R.P.; Herrmann, Bent; Krag, L.A. (Journal article; Tidsskriftartikkel, 2020-08-12)
      The North Sea brown shrimp (<i>Crangon crangon</i> Linnaeus, 1758) fishery became Marine Stewardship Council (MSC) certified in 2017. As part of the certification, the fishermen proposed to incrementally increase the mesh size of the codend used from 22 mm to 26 mm. As this increase in mesh size could result in a substantial loss of marketable sized brown shrimp (shrimp with total length equal or ...
    • Testing of hook sizes and appendages to reduce yelloweye rockfish bycatch in a Pacific halibut longline fishery 

      Lomeli, Mark Joseph Max; Wakefield, W. Waldo; Abele, Meagan; Dykstra, Claude L.; Herrmann, Bent; Stewart, Ian J.; Christie, Gregory C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-03)
      In Pacific halibut (Hippoglossus stenolepis) longline fisheries in the eastern North Pacific Ocean bycatch of yelloweye rockfish (Sebastes ruberrimus) is a concern as their stock status along the U.S. West Coast is “rebuilding” from being “overfished”, the southeast Alaska stock has shown a ∼60% decline since at least 1994 and through 2015 where it stabilized, and the Canadian stock has been recently ...
    • Th17 master transcription factors RORα and RORγ regulate the expression of IL-17C, IL-17D and IL-17F in Cynoglossus semilaevis 

      Chi, Heng; Bøgwald, Jarl; Dalmo, Roy Ambli; Zhang, Wenjie; Hu, Yong-hua (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-10)
      The RAR-related orphan receptors (RORs) are members of the nuclear receptor family of intracellular transcription factors. In this study, we examined the regulatory properties of RORα (CsRORα) and RORγ (CsRORγ) in tongue sole (Cynoglossus semilaevis). CsRORα and CsRORγ expression was detected in major lymphoid organs and altered to significant extents after bacterial and viral infection. CsRORα ...
    • Thee level of eicosapentaenoic (EPA),but not docosahexaenoic acid (DHA) is related to formulation and concentration of EPA and DHA in feed 

      Seternes, Tore; Johansson, Gunhild S.; Evje, Iselin; Olsen, Ragnar Ludvig (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-22)
      The present study investigated how the concentration of PUFA in blood and muscle of Atlantic salmon (<i>Salmo salar</i> L.) changed when fed 4 diets containing very different amounts of LC-PUFA in fresh water for 84 days. The n-3 LC-PUFA constituted 4.4, 24.2, 18.4, and 51.5% of the total fatty acids in the diets made with rapeseed oil, anchoveta oil, a combination of rapeseed oil (60%) and anchoveta ...
    • Thermal injuries in Atlantic salmon in a pilot Laboratory trial 

      Gismervik, Kristine; Gåsnes, Siri Kristine; Gu, Jinni; Stien, Lars Helge; Madaro, Angelico; Nilsson, Jonatan (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-27)
      Thermal delousing is a new method for removing sea lice from farmed Atlantic salmon (<i>Salmo salar</i> L). We investigated thermally-related tissue injuries in Atlantic salmon in a pilot laboratory trial to describe the acute effect of high water temperatures (34–38 °C). Acute tissue injuries in gills, eyes, brain and possible also nasal cavity and thymus were seen in salmon exposed to water ...
    • To denoise or to cluster, that is not the question: optimizing pipelines for COI metabarcoding and metaphylogeography 

      Antich, Adrià; Palacin, Creu; Wangensteen, Owen S.; Turon, Xavier (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-05)
      <i>Background</i> - The recent blooming of metabarcoding applications to biodiversity studies comes with some relevant methodological debates. One such issue concerns the treatment of reads by denoising or by clustering methods, which have been wrongly presented as alternatives. It has also been suggested that denoised sequence variants should replace clusters as the basic unit of metabarcoding ...
    • To tell or not to tell: Preference elicitation with and without emphasis on scientific uncertainty 

      Aanesen, Margrethe; Armstrong, Claire W.; Borch, Trude Kristin; Fieler, Reinhold; Hausner, Vera Helene; Kipperberg, Gorm; Lindhjem, Henrik; Navrud, Ståle (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-01)
      Decisions about the optimal use of coastal and marine resources must be taken under high uncertainty about environmental impacts and may conflict with public perception of the risk associated with current blue growth initiatives. In a discrete choice experiment conducted in valuation workshops in five communities in Arctic Norway, we examine public preferences for various aquaculture expansion paths. ...
    • Torsk fra merd: Pre-rigor produksjon av loins med skinn 

      Kristoffersen, Silje; Kristiansen, Frank; Eilertsen, Guro; Olsen, Ragnar Ludvig (Research report; Forskningsrapport, 2009-03)
      I dette forsøket ble torsk fanget levende og lagret i merd hvor den ble fôret med hhv. lodde og kommersielt torskefôr i 3 måneder. Etter skånsom slakting og utblødning i 30 minutter, ble fisken sløyd og de biologiske data registrert før maskinell filetering enten pre-rigor (innen 2 timer etter død) og post-rigor (etter 4 dagers is-lagring av sløyd fisk). Det ble produsert ryggfileter (Loins) enten ...
    • Total Catch of a Red-Listed Marine Species Is an Order of Magnitude Higher than Official Data 

      Kleiven, Alf Ring; Olsen, Esben Moland; Vølstad, Jon Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Accurate information on total catch and effort is essential for successful fisheries management. Officially reported landings, however, may be underestimates of total catch in many fisheries. We investigated the fishery for the nationally red-listed European lobster (Homarus gammarus) in south-eastern Norway. Probability-based strip transect surveys were used to count buoys in the study area in ...
    • Tourism in Marine Protected Areas: A view from Nha Trang Bay, Vietnam 

      Pham-Do, Kim Hang; Pham, Thi Thanh Thuy (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-25)
      Tourism development is considered a key accompanying strategy in creating alternative livelihood options for the communities living in and adjacent to the Marine Protected Areas. This paper examines the socioeconomic characteristics of the Nha Trang Bay protected area to determine the factors that influence the decision to participate in tourism sectors, and analyse whether these decisions would ...
    • Tourism in marine protected areas: Can it be considered as an alternative livelihood for local communities? 

      Pham, Thi Thanh Thuy (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-03)
      The promotion of tourism has been considered to be a key strategy in reducing people's dependence on marine resources and for creating alternative livelihoods for the communities living in Marine Protected Areas (MPAs). This paper studies the determinants for the decision of participation in tourism-related activities and examines whether tourism could be regarded as an alternative livelihood for ...
    • Towards an Iberian DNA barcode reference library of freshwater macroinvertebrates and fishes 

      Múrria, Cesc; Väisänen, Leif O. S.; Somma, Simona; Wangensteen Fuentes, Owen Simon; Arnedo, Miquel A.; Prat, Narcís (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Freshwater macroinvertebrates and fishes are focal groups in major ecosystem biomonitoring programs in the Iberian Peninsula. Yet, their use as bioindicators is sometimes constrained by the time and cost needed for sorting macroinvertebrates specimens and their challenging taxonomic identification, and the huge sampling procedures for capturing rare or incipient fish species, respectively. Given the ...