• Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp. 

      Pheiffer, Fazlin; Schneider, Yannik Karl Heinz; Hansen, Espen Holst; Andersen, Jeanette Hammer; Isaksson, Johan Mattias; Busche, Tobias; Rückert, Christian; Kalinowski, Jörn; van Zyl, Leonardo; Trindade, Marla (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-20)
      Bacterial symbionts of marine invertebrates are rich sources of novel, pharmaceutically relevant natural products that could become leads in combatting multidrug-resistant pathogens and treating disease. In this study, the bioactive potential of the marine invertebrate symbiont Thalassomonas actiniarum was investigated. Bioactivity screening of the strain revealed Gram-positive specific antibacterial ...