Blar i forfatter Artikler, rapporter og annet (Norges fiskerihøgskole) "Zhan, Wenbin"

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    • Anti-microbial activity and immunomodulation of recombinant hepcidin 2 and NK-lysin from flounder (Paralichthys olivaceus) 

      Li, Xinyu; Chi, Heng; Dalmo, Roy Ambli; Tang, Xiaoqian; Xing, Jing; Sheng, Xiuzhen; Zhan, Wenbin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-21)
      Infections due to pathogens impact global aquaculture economy, where diseases caused by bacteria should be in particular focus due to antibiotic resistance. Hepcidin and NK-lysin are important innate immune factors having potential to be exploited as alternatives to antibiotics due to their antimicrobial activity and immunomodulatory capacity. In this study, the recombinant proteins of hepcidin 2 ...

    • Characterization of myeloperoxidase and its contribution to antimicrobial effect on extracellular traps in flounder (Paralichthys olivaceus) 

      Gan, Qiujie; Chi, Heng; Dalmo, Roy Ambli; Meng, Xianghu; Tang, Xiaoqian; Xing, Jing; Sheng, Xiuzhen; Zhan, Wenbin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-26)
      Myeloperoxidase (MPO) is a cationic leukocyte haloperoxidase and together with other proteins, they possess activities against various microorganisms and are involved in extracellular trap (ET) formation. The present work describes the gene and deduced protein sequences, and functions of MPO in flounder (PoMPO). The PoMPO possesses a 2313 bp open reading frame (ORF) that encodes a protein of 770 ...

    • Vaccine Adjuvants Induce Formation of Intraperitoneal Extracellular Traps in Flounder (Paralichthys olivaceus) 

      Li, Qian; Chi, Heng; Shi, Xueyan; Gan, Qiujie; Dalmo, Roy Ambli; Sun, Yuan-Yuan; Tang, Xiaoqian; Xing, Jing; Sheng, Xiuzhen; Zhan, Wenbin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-30)
      Adjuvants are used to increase the strength, quality, and duration of the immune response of vaccines. Neutrophils are the first immune cells that arrive at the injection site and can release DNA fibers together with granular proteins, so-called neutrophil extracellular traps (NETs), to entrap microbes in a sticky matrix of extracellular chromatin and microbicidal agents. Similar extracellular ...