Browsing Artikler, rapporter og annet (Norges fiskerihøgskole) by Author "Albrigtsen, Marte"

Now showing items 1-3 of 3

    • Bioactivity Screening of Microalgae for Antioxidant, Anti-Inflammatory, Anticancer, Anti-Diabetes, and Antibacterial Activities 

      Lauritano, Chiara; Andersen, Jeanette hammer; Hansen, Espen; Albrigtsen, Marte; Escalera, Laura; Esposito, Francesco; Helland, Kirsti; Østnes Hanssen, Kine; Romano, Giovanna; Ianora, Adrianna (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-10)
      Marine microalgae are considered a potentially new and valuable source of biologically active molecules for applications in the food industry as well as in the pharmaceutical, nutraceutical, and cosmetic sectors. They can be easily cultured, have short generation times and enable an environmentally-friendly approach to drug discovery by overcoming problems associated with the over-utilization ...

    • A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma 

      Haugaard-Kedström, Linda M.; Clemmensen, Louise S.; Sereikaite, Vita; Jin, Zeyu; Fernandes, Eduardo F. A.; Wind, Bianca; Abalde-Gil, Flor; Daberger, Jan; Vistrup-Parry, Maria; Aguilar-Morante, Diana; Leblanc, Raphael; Egea-Jimenez, Antonio L.; Albrigtsen, Marte; Jensen, Kamilla E.; Jensen, Thomas M. T.; Ivarsson, Ylva; Vincentelli, Renaud; Hamerlik, Petra; Andersen, Jeanette Hammer; Zimmermann, Pascale; Lee, Weonate; Strømgaard, Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-27)
      Despite the recent advances in cancer therapeutics, highly aggressive cancer forms, such as glioblastoma (GBM), still have very low survival rates. The intracellular scaffold protein syntenin, comprising two postsynaptic density protein-95/discs-large/zona occludens-1 (PDZ) domains, has emerged as a novel therapeutic target in highly malignant phenotypes including GBM. Here, we report the development ...

    • Synthesis and Evaluation of the Tetracyclic Ring-System of Isocryptolepine and Regioiso-Mers for Antimalarial, Antiproliferative and Antimicrobial Activities 

      Håheim, Katja Stangeland; Lindback, Emil; Tan, Kah Ni; Albrigtsen, Marte; Helgeland, Ida Therese Urdal; Clemence, Lauga; Matringe, Theodora; Kennedy, Emily K.; Andersen, Jeanette Hammer; Avery, Vicky M.; Sydnes, Magne Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-30)
      A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities. The novel hydroiodide salts 10 and 21 showed the most promising antiplasmodial inhibition, with compound 10 displaying higher selectivity than the employed standards. The antiproliferative assay revealed novel pyridophenanthridine ...