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dc.contributor.authorSheikh, Mashhood Ahmed
dc.date.accessioned2019-01-30T10:39:36Z
dc.date.available2019-01-30T10:39:36Z
dc.date.issued2018-06-05
dc.description.abstract<p><i>Objective</i>: Physical inactivity is a major public health problem associated with an increased risk of several psychiatric and physical conditions. This study investigated the association between leisure time physical activity (PA) and incident use of prescription tranquilizers in a regionally representative and prospective cohort.</p> <p><i>Methods</i>: A total of 4043 men and women (mean age: 61.3 years; 57% women) from the Tromsø Study were followed for six years. Leisure time PA was captured at baseline. Psychiatric morbidity was measured by use of prescription tranquilizers, captured at both baseline and follow-up. Leisure time PA at baseline was used as a predictor of subsequent (incident) use of prescription tranquilizers. We used multinomial regression models and Poisson regression models to estimate relative risk-ratios (RRRs), and relative risks (RRs), respectively, and their corresponding 95% confidence intervals (CIs).</p> <p><i>Results</i>: In the fully-adjusted model, accounting for socio-demographic factors, parental history of psychopathology, years of education, smoking, respondent's psychopathology at baseline, and occupational PA, a lower leisure time PA conferred a 41% increased risk of incident use of prescription tranquilizers at follow-up (RR = 1.41, 95% CI: 1.09, 1.83; p = 0.010).</p> <p><i>Conclusions</i>: These findings suggest that physical inactivity increases the risk of psychiatric morbidity (albeit, measured via use of prescription tranquilizers). Future regionally representative and longitudinal research is required to confirm/refute our findings and explore underlying mechanisms.en_US
dc.descriptionAccepted manuscript version, licensed <a href=http://creativecommons.org/licenses/by-nc-nd/4.0/> CC BY-NC-ND 4.0.</a> Published version available at <a href=https://doi.org/10.1016/j.jad.2018.06.010> https://doi.org/10.1016/j.jad.2018.06.010</a>.en_US
dc.identifier.citationSheikh, M.A. (2018). Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study. <i>Journal of Affective Disorders</i>, 238, 327-335. https://doi.org/10.1016/j.jad.2018.06.010en_US
dc.identifier.cristinIDFRIDAID 1626181
dc.identifier.doi10.1016/j.jad.2018.06.010
dc.identifier.issn0165-0327
dc.identifier.issn1573-2517
dc.identifier.urihttps://hdl.handle.net/10037/14559
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalJournal of Affective Disorders
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800en_US
dc.subjectPhysical activityen_US
dc.subjectTranquilizeren_US
dc.subjectPsychotropicen_US
dc.subjectPsychiatric morbidityen_US
dc.titleLeisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based studyen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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