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dc.contributor.authorBakken, Toril
dc.contributor.authorBraaten, Tonje
dc.contributor.authorOlsen, Anja
dc.contributor.authorHjartåker, Anette
dc.contributor.authorLund, Eiliv
dc.contributor.authorSkeie, Guri
dc.date.accessioned2019-02-18T15:15:05Z
dc.date.available2019-02-18T15:15:05Z
dc.date.issued2018-05-17
dc.description.abstractAccording to World Cancer Research Fund International/American Institute for Cancer Research, it is ‘probable’ that dairy products decrease the risk of colorectal cancer (CRC). However, meta-analyses restricted to women have not shown associations between milk intake and risk of CRC. The aim of this study was to examine the association between milk intake and risk of CRC, colon cancer and rectal cancer among women. Data from 81 675 participants in the Norwegian Women and Cancer Cohort Study were included, and multivariable Cox proportional hazard regression models were used to investigate milk intake using two different analytical approaches: one that included repeated measurements and one that included baseline measurements only (872 and 1084 CRC cases, respectively). A weak inverse association between milk intake and risk of colon cancer may be indicated both in repeated measurements analyses and in baseline data analyses. Hazard ratios (HR) for colon cancer of 0·80 (95 % CI 0·62, 1·03, <i>P</i> <sub>trend</sub> 0·07) and 0·81 (95 % CI 0·64, 1·01, <i>P</i> <sub>trend</sub> 0·03) and HR for rectal cancer of 0·97 (95 % CI 0·67, 1·42, <i>P</i> <sub>trend</sub> 0·92) and 0·71 (95 % CI 0·50, 1·01, <i>P</i> <sub>trend</sub> 0·03) were found when comparing the high with the no/seldom milk intake group in energy-adjusted multivariable models. Our study indicates that there may be a weak inverse association between milk intake and risk of colon cancer among women. The two analytical approaches yielded different results for rectal cancer and hence CRC. Our study indicates that the use of single or repeated measurements in analyses may influence the results.en_US
dc.descriptionSource at <a href=https://doi.org/10.1017/S0007114518000752>https://doi.org/10.1017/S0007114518000752.</a>en_US
dc.identifier.citationBakken, T., Braaten, T., Olsen, A., Hjartåker, A., Lund, E. & Skeie, G. (2018). Milk and risk of colorectal, colon and rectal cancer in the Norwegian Women and Cancer (NOWAC) Cohort Study. <i>British Journal of Nutrition, 119</i>(11), 1274-1285. https://doi.org/10.1017/S0007114518000752en_US
dc.identifier.cristinIDFRIDAID 1592714
dc.identifier.doi10.1017/S0007114518000752
dc.identifier.issn0007-1145
dc.identifier.issn1475-2662
dc.identifier.urihttps://hdl.handle.net/10037/14710
dc.language.isoengen_US
dc.publisherCambridge University Press (CUP)en_US
dc.relation.journalBritish Journal of Nutrition
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en_US
dc.subjectColorectal canceren_US
dc.subjectMilken_US
dc.subjectProspective cohortsen_US
dc.subjectRepeated measurementsen_US
dc.subjectWomenen_US
dc.titleMilk and risk of colorectal, colon and rectal cancer in the Norwegian Women and Cancer (NOWAC) Cohort Studyen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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