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dc.contributor.authorOvery, David P.
dc.contributor.authorRämä, Teppo
dc.contributor.authorOosterhuis, Rylee
dc.contributor.authorWalker, Allison K.
dc.contributor.authorPang, Ka-Lai
dc.date.accessioned2019-10-16T12:10:06Z
dc.date.available2019-10-16T12:10:06Z
dc.date.issued2019-01-10
dc.description.abstractDespite the rapid development of molecular techniques relevant for natural product research, culture isolates remain the primary source from which natural products chemists discover and obtain new molecules from microbial sources. Techniques for obtaining and identifying microbial isolates (such as filamentous fungi) are thus of crucial importance for a successful natural products’ discovery program. This review is presented as a “best-practices guide” to the collection and isolation of marine fungi for natural products research. Many of these practices are proven techniques used by mycologists for the isolation of a broad diversity of fungi, while others, such as the construction of marine baiting stations and the collection and processing of sea foam using dilution to extinction plating techniques, are methodological adaptations for specialized use in marine/aquatic environments. To this day, marine fungi, <i>Sensu stricto</i>, remain one of the few underexplored resources of natural products. Cultivability is one of the main limitations hindering the discovery of natural products from marine fungi. Through encouraged collaboration with marine mycologists and the sharing of historically proven mycological practices for the isolation of marine fungi, our goal is to provide natural products chemists with the necessary tools to explore this resource in-depth and discover new and potentially novel natural products.en_US
dc.descriptionSource at <a href=https://doi.org/10.3390/md17010042>https://doi.org/10.3390/md17010042</a>.en_US
dc.identifier.citationOvery, D.P., Rämä, T., Oosterhuis, R., Walker, A.K. & Pang, K.L. (2019). The Neglected Marine Fungi, <i>Sensu stricto</i>, and Their Isolation for Natural Products’ Discovery. <i>Marine Drugs, 17</i>(1), 42. https://doi.org/10.3390/md17010042en_US
dc.identifier.cristinIDFRIDAID 1655076
dc.identifier.doi10.3390/md17010042
dc.identifier.issn1660-3397
dc.identifier.urihttps://hdl.handle.net/10037/16416
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalMarine Drugs
dc.relation.projectIDinfo:eu-repo/grantAgreement/RCN/BIOTEK2021/269425/Norway/Digital discovery of antimicrobial molecules from marine Arctic resources with reduced risk of triggering resistance//en_US
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Mathematics and natural science: 400::Zoology and botany: 480::Marine biology: 497en_US
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480::Marinbiologi: 497en_US
dc.subjectmarine fungien_US
dc.subjectisolationen_US
dc.subjectculturingen_US
dc.subjectidentificationen_US
dc.subjectnatural productsen_US
dc.subjectsecondary metabolitesen_US
dc.titleThe Neglected Marine Fungi, Sensu stricto, and Their Isolation for Natural Products’ Discoveryen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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