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dc.contributor.authorBaiju, Nikita
dc.contributor.authorAcharya, Ganesh
dc.contributor.authorD'Antonio, Francesco
dc.contributor.authorBerg, Rigmor
dc.date.accessioned2020-01-02T12:38:21Z
dc.date.available2020-01-02T12:38:21Z
dc.date.issued2019-08-31
dc.description.abstract<i>Background</i> - For many women, the need for multiple clinical visits is a barrier to medical abortion.<p> <p><i>Objectives</i> - We assessed the effectiveness, safety, and acceptability of self‐assessment of the outcome of medical abortion completed at home versus routine clinic follow up after medical abortion.<p> <p><i>Search strategy</i> - We searched databases such as MEDLINE, Embase, and CENTRAL to find studies published in 1991–2018.Selection criteria Eligible studies included women of reproductive age who had undergone a medical abortion that was completed at home. The intervention and self‐assessment of the outcome of medical abortion done by urine pregnancy tests kits by women at home was compared with routine medical follow up at a clinic.<p> <p><i>Data collection and analysis</i> - Two researchers completed the study selection, data extraction, critical appraisal, and assessment of the evidence. The outcomes were successful complete abortions, side effects and complications, and acceptability. We performed meta‐analyses when possible and GRADE to ascertain the certainty of the evidence. The protocol was registered in PROSPERO (CRD42017055316).<p> <p><i>Main results</i> - Four randomised controlled trials (RCTs; n = 5493) met our inclusion criteria. The pooled analysis from all studies showed no significant difference in complete abortion rates between self‐assessment and routine clinic follow up: RR = 1.00, 95% CI 0.99–1.01. The ongoing pregnancy rates were similar and the pooled results for the safety outcomes showed no significant differences between the groups. There was a significantly greater preference for self‐assessment as the follow‐up method.<p> <p><i>Conclusions</i> - The effectiveness, safety, and acceptability of self‐assessment of the outcome of medical abortion completed at home are not inferior to routine clinic follow up.en_US
dc.identifier.citationBaiju N, Acharya G, D'Antonio F, Berg RC. Effectiveness, safety and acceptability of self-assessment of the outcome of first-trimester medical abortion: a systematic review and meta-analysis. BJOG: an International Journal of Obstetrics and Gynaecology. 2019;126(13):1536-1544en_US
dc.identifier.cristinIDFRIDAID 1747124
dc.identifier.doi10.1111/1471-0528.15922
dc.identifier.issn1470-0328
dc.identifier.issn1471-0528
dc.identifier.urihttps://hdl.handle.net/10037/17009
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalBJOG: an International Journal of Obstetrics and Gynaecology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2019 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en_US
dc.titleEffectiveness, safety and acceptability of self-assessment of the outcome of first-trimester medical abortion: a systematic review and meta-analysisen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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