• Efficient palladium-catalyzed electrocarboxylation enables late-stage carbon isotope labelling 

      Batista, Gabriel M. F.; Ebenbauer, Ruth; Day, Craig S.; Bergare, Jonas; Neumann, Karoline; Hopmann, Kathrin Helen; Elmore, Charles; Rosas-Hernandez, Alonso; Skrydstrup, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-22)
      Carbon isotope labelling of bioactive molecules is essential for accessing the pharmacokinetic and pharmacodynamic properties of new drug entities. Aryl carboxylic acids represent an important class of structural motifs ubiquitous in pharmaceutically active molecules and are ideal targets for the installation of a radioactive tag employing isotopically labelled CO<sub>2</sub>. However, direct isotope ...
    • Lignocellulose Conversion via Catalytic Transformations Yields Methoxyterephthalic Acid Directly from Sawdust 

      Pedersen, Simon S.; Batista, Gabriel M. F.; Henriksen, Martin L.; Hammershøj, Hans Christian D.; Hopmann, Kathrin Helen; Skrydstrup, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-10)
      Poly(ethylene terephthalate) polyester represents the most common class of thermoplastic polymers widely used in the textile, bottling, and packaging industries. Terephthalic acid and ethylene glycol, both of petrochemical origin, are polymerized to yield the polyester. However, an earlier report suggests that polymerization of methoxyterephthalic acid with ethylene glycol provides a methoxy-polyester ...