Blar i forfatter Artikler, rapporter og annet (kjemi) "Halskau, Øyvind"

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    • The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection 

      Dobrovolska, Olena; Brilkov, Maxim; Madeleine, Noëlly; Ødegaard-Fougner, Øyvind; Strømland, Øyvind; Martin, Stephen R.; De Marco, Valeria; Christodoulou, Evangelos; Teigen, Knut; Isaksson, Johan; Underhaug, Jarl; Reuter, Nathalie; Aalen, Reidunn B.; Aasland, Rein; Halskau, Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-21)
      Chromatin post‐translational modifications are thought to be important for epigenetic effects on gene expression. Methylation of histone N‐terminal tail lysine residues constitutes one of many such modifications, executed by families of histone lysine methyltransferase (HKMTase). One such protein is ASHH2 from the flowering plant <i>Arabidopsis thaliana</i>, equipped with the interaction domain, CW, ...

    • Contrasting the phospholipid profiles of two neoplastic cell lines reveal a high PC:PE ratio for SH-SY5Y cells relative to A431 cells 

      Bariås, Espen; Jakubec, Martin; Førsund, Elise; Hjørnevik, Linda Veka; Lewis, Aurelia Eva; Halskau, Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-14)
      Lipids have been implicated in Parkinson's Disease (PD). We therefore studied the lipid profile of the neuroblastoma SH-SY5Y cell line, which is used extensively in PD research and compared it to that of the A431 epithelial cancer cell line. We have isolated whole cell extracts (WC) and plasma membrane (PM) fractions of both cell lines. The isolates were analyzed with 31P NMR. We observed a significant ...