Blar i forfatter Artikler, rapporter og annet (kjemi) "Karlsen, Eskil André"
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Anti-Colonization Effect of Au Surfaces with Self-Assembled Molecular Monolayers Functionalized with Antimicrobial Peptides on S. epidermidis
Karlsen, Eskil André; Stensen, Wenche; Juskewitz, Eric; Svenson, Johan; Berglin, Mattias; Svendsen, John Sigurd Mjøen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)Medical devices with an effective anti-colonization surface are important tools for combatting healthcare-associated infections. Here, we investigated the anti-colonization efficacy of antimicrobial peptides covalently attached to a gold model surface. The gold surface was modified by a self-assembled polyethylene glycol monolayer with an acetylene terminus. The peptides were covalently connected ... -
Preventing E. coli Biofilm Formation with Antimicrobial Peptide-Functionalized Surface Coatings: Recognizing the Dependence on the Bacterial Binding Mode Using Live-Cell Microscopy
Hansson, Adam; Karlsen, Eskil André; Stensen, Wenche Gunvor B; Svendsen, John Sigurd Mjøen; Berglin, Mattias; Lundgren, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-31)Antimicrobial peptides (AMPs) can kill bacteria by destabilizing their membranes, yet translating these molecules’ properties into a covalently attached antibacterial coating is challenging. Rational design efforts are obstructed by the fact that standard microbiology methods are ill-designed for the evaluation of coatings, disclosing few details about why grafted AMPs function or do not ...