Blar i forfatter Artikler, rapporter og annet (kjemi) "Rainsford, Philip Ben"

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    • Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis 

      Rainsford, Philip Ben; Rylandsholm, Fredrik G.; Jakubec, Martin; Silk, Mitchell; Juskewitz, Eric; Ericson, Johanna Ulrica; Svendsen, John Sigurd Mjøen; Engh, Richard Alan; Isaksson, Johan Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-03)
      One strategy to combat antimicrobial resistance is the discovery of new classes of antibiotics. Most antibiotics will at some point interact with the bacterial membrane to either interfere with its integrity or to cross it. Reliable and efficient tools for determining the dissociation constant for membrane binding (K<sub><i>D</sub></i>) and the partitioning coefficient between the aqueous- and ...