Browsing Artikler, rapporter og annet (kjemi) by Author "Sydnes, Magne Olav"
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The crystal structure of haemoglobin from Atlantic cod
Helland, Ronny; Bjørkeng, Eva katrin; Rothweiler, Ulli; Sydnes, Magne Olav; Pampanin, Daniela Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-16)The crystal structure of haemoglobin from Atlantic cod has been solved to 2.54 A˚ resolution. The structure consists of two tetramers in the crystallographic asymmetric unit. The structure of haemoglobin obtained from one individual cod suggests polymorphism in the tetrameric assembly. -
Regiodivergent Synthesis of 11H-Indolo[3,2-c]quinolines and Neocryptolepine from a Common Starting Material
Håheim, Katja Stangeland; Lund, Bjarte Aarmo; Sydnes, Magne Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-23)A large number of diversely functionalized analogs of the bioactive natural products neocryptolepine and isocryptolepine have been prepared from a series of 3-bromoquinoline derivatives. The neocryptolepines were obtained by a Pd<sup>0</sup>-catalyzed C−C bond coupling followed by C−N bond formation in yields up to 80 %, whereas the indoloquinolines were prepared by a Suzuki-Miyaura cross-coupling ... -
Total synthesis of tubastrine and 3-dehydroxy tubastrine by microwave-assisted cross-coupling reactions
Lorentzen, Marianne; Bayer, Annette; Sydnes, Magne Olav; Jørgensen, Kåre Bredeli (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-03)The first syntheses of tubastrine and 3-dehydroxy tubastrine are described. The target compounds were prepared in four consecutive steps from commercially available starting materials. The central scaffold was formed by a microwave-assisted C–N cross-coupling reaction between 1,3-bis(<i>tert</i>-butoxycarbonyl)-guanidine and (<i>E</i>)-((4-(2-iodovinyl)-1,2-phenylene)bis(oxy))bis(<i>tert</i>-butyl ...