• DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes 

      Zhu, Bangfu; Parsons, Tom; Stensen, Wenche Gunvor Berg; Svendsen, John Sigurd Mjøen; Fugelli, Anders; Hodge, James W.L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-19)
      Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the community. Despite the pathological processing of genes such as Amyloid Precursor Protein (APP) into Amyloid-β and Microtubule Associated Protein Tau (MAPT) gene, into hyperphosphorylated Tau tangles being ...