Blar i forfatter Mastergradsoppgaver i farmasi "Brown, Rosaline"
-
Functional analysis of signaling pathways activated by Anisomycin and Dexamethasone in two different breast cancer cell lines
Brown, Rosaline (Mastergradsoppgave; Master thesis, 2022-05-12)While targeted therapy exists for ER-positive breast cancers, the treatment option for TNBC is conventional chemotherapy giving a poorer prognosis. It is therefore of interest to study molecular mechanisms and differences between MCF7 (ER-positive) and MDA-MB-231 (ER, PR, and HER2- negative). These cell lines are in vitro representative models for luminal A (non-aggressive) and basal-like (aggressive) ...