Blar i forfatter Mastergradsoppgaver i farmasi "Elvheim, Iselin Sørstad"
-
Design, synthesis and structural studies of relaxin receptor modulators
Elvheim, Iselin Sørstad (Master thesis; Mastergradsoppgave, 2011-06)The relaxin family of peptides consists of seven structurally related peptides, with a wide variety of biological functions, ranging from involvement in reproductive processes to functions as neuroendocrine modulators. Because of the complex, two-chained structure of the relaxins, and their lack of specificity for the various relaxin family receptors (RXFPs), design of simpler, more selective ...