Blar i forfatter Mastergradsoppgaver i farmasi "Schäfer, Helene Bekkeli"
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A study of Fez1 and Fez2: Localization and knock-out
Schäfer, Helene Bekkeli (Master thesis; Mastergradsoppgave, 2016-05-11)Autophagy is a fundamental cellular process where cell components get digested in autolysosomes and are recycled. Dysregulation of autophagy is involved in major diseases like cancer, neurodegeneration, inflammation and ischemia. In this thesis we have worked with fasciculation and elongation zeta (Fez) proteins, which are reported to inhibit autophagy. There are at least two mammalian Fez proteins, ...