dc.contributor.author | Andersen, Eivind | |
dc.contributor.author | Bang-Kittilsen, Gry | |
dc.contributor.author | Bigseth, Therese Torgersen | |
dc.contributor.author | Egeland, Jens | |
dc.contributor.author | Holmen, Tom Langerud | |
dc.contributor.author | Martinsen, Egil Wilhelm | |
dc.contributor.author | Stensrud, Trine | |
dc.contributor.author | Engh, John | |
dc.date.accessioned | 2020-09-18T11:23:09Z | |
dc.date.available | 2020-09-18T11:23:09Z | |
dc.date.issued | 2020-08-27 | |
dc.description.abstract | <i>Background</i> - Exercise may improve cardiorespiratory fitness in people with schizophrenia, however, possible condition-specific cardiorespiratory disadvantages, a scarcity of methodologically sound studies, and conflicting results raise questions about the effect of exercise on maximal oxygen uptake (VO<sub>2max</sub>) in this group. The primary aim of this study, therefore, was to investigate the effect of high-intensity interval training on VO<sub>2max</sub> in people with schizophrenia. Second, we sought to determine whether the intervention would have an effect on general physical activity (PA) level and body composition.<p><p>
<i>Methods</i> - Eighty-two patients with schizophrenia were randomly assigned to supervised high-intensity interval training or computer gaming skills training, performed twice a week for 12 weeks. Oxygen uptake was measured directly, during a maximum exercise session on a treadmill. PA level were assessed using ActiGraph accelerometer, and body composition was assessed by bioelectrical impedance. Differences between groups were assessed by analysis of variance using a univariate general linear model.<p><p>
<i>Results</i> - There were no significant differences between the groups on any of the cardiorespiratory variables neither at baseline nor after the program. There were also no significant within-group differences in any of the cardiorespiratory fitness variables between the baseline and post-program time points, despite that 61% of the participants performing high-intensity interval training showed a significant increase in workload on the treadmill. However, 47% of the participants in the high-intensity interval training group had a ≥ 5% increase in VO<sub>2max</sub>. Participants supervised by mental health care providers with PA competence (e.g. rehabilitation center staff, sport scientist, physical trainer) had a much larger increase in VO<sub>2max</sub> compared to participants supervised by mental health workers without such competence, and when adding PA competence to the model, the intervention group increased VO<sub>2max</sub> significantly compared to the comparison group. The intervention had no significant effect on PA level or body composition.<p><p>
<i>Conclusions</i> - The intervention did not improve VO<sub>2max</sub>, PA level or body composition but succeeded in increasing workload on the treadmill. With regard to VO<sub>2max</sub>, approximately half of the patients may be considered responders. | en_US |
dc.identifier.citation | Andersen E, Bang-Kittilsen G, Bigseth T, Egeland J, Holmen TL, Martinsen EW, Stensrud T, Engh J. Effect of high-intensity interval training on cardiorespiratory fitness, physical activity
and body composition in people with
schizophrenia: a randomized controlled
trial. BMC Psychiatry. 2020;20:425 | en_US |
dc.identifier.cristinID | FRIDAID 1825878 | |
dc.identifier.doi | 10.1186/s12888-020-02827-2 | |
dc.identifier.issn | 1471-244X | |
dc.identifier.uri | https://hdl.handle.net/10037/19432 | |
dc.language.iso | eng | en_US |
dc.publisher | BMC | en_US |
dc.relation.journal | BMC Psychiatry | |
dc.rights.accessRights | openAccess | en_US |
dc.rights.holder | Copyright 2020 The Author(s) | en_US |
dc.subject | VDP::Medical disciplines: 700 | en_US |
dc.subject | VDP::Medisinske Fag: 700 | en_US |
dc.title | Effect of high-intensity interval training on cardiorespiratory fitness, physical activity and body composition in people with schizophrenia: a randomized controlled trial | en_US |
dc.type.version | publishedVersion | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |