Blar i forfatter Mastergradsoppgaver i biologi (Helsefak) "Mauseth, Brynjar"
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Oncolytic Activity and Mechanisms of Action by a small β2,2-amino acid derivative LTX-401
Mauseth, Brynjar (Master thesis; Mastergradsoppgave, 2015-05-11)Antimicrobial peptides are part of the innate immune defence of many organisms and represent a novel class of therapeutics due to their broad-spectrum activities, including cytotoxic activity against cancer cells. It has recently been reported that small antimicrobial β2,2-amino acid derivatives (Mw<500), such as LTX-401, possess potent anticancer activity against Ramos human Burkitt’s lymphoma ...