Blar i forfatter Mastergradsoppgaver i biologi (Helsefak) "van Ligtenberg, Lennart Maximilian"
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Exploration of rabbit integrin β3 as a possible immune-tolerizing agent to prevent foetal and neonatal alloimmune thrombocytopenia.
van Ligtenberg, Lennart Maximilian (Mastergradsoppgave; Master thesis, 2020-08-07)Foetal and neonatal alloimmune thrombocytopenia (FNAIT) is a disease caused by the production of antibodies by the mother to the platelets of the foetus. The alloimmune response is caused by a P33L substitution in the Human Platelet Antigen-1a (HPA-1a) in a homo- or heterozygous HPA-1a foetus, in a homozygous HPA-1b+ mother. Maternal antibodies are produced by activated HPA-1a specific T-cells able ...