Identification of Bioactive Molecules from Arctic Marine Arthrobacter Isolates

Abstract

In this study, five isolated Arctic marine bacteria of the genus Arthrobacter were cultivated under different temperatures and growth media. Employing the “One Strain-Many Compounds” (OSMAC) approach, in an attempt to produce novel and interesting compounds with potential bioactivity by triggering different metabolic pathways. The motivation for this thesis was to discover new types of arthrobacilins produced by Arctic marine Arthrobacter isolates and identify novel secondary metabolites with potential bioactivity. Another motivation was to gain experience with the genus Arthrobacter, and Actinobacteria as a phylum in general.