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dc.contributor.authorIbrahim, Mustafa
dc.contributor.authorHedlundh, Urban
dc.contributor.authorSernert, Ninni
dc.contributor.authorMeknas, Khaled
dc.contributor.authorHaag, Lars
dc.contributor.authorMovin, Tomas
dc.contributor.authorPapadogiannakis, Nikos
dc.contributor.authorKartus, Jüri-Tomas
dc.date.accessioned2021-09-07T07:29:35Z
dc.date.available2021-09-07T07:29:35Z
dc.date.issued2021-05-26
dc.description.abstract<i>Background</i> - Despite gluteus medius (GMED) tendinosis being relatively common, its presence in association with hip osteoarthritis (OA) or total hip arthroplasty (THA) is not well studied. It was hypothesized that more tendon degeneration would be found in patients with OA of the hip and in those that had undergone THA than that in a control group.<br><br> <i>Methods</i> - One hundred patients were included between 2016 and 2019 and were included into 4 groups; the patients were undergoing revision surgery in two groups and primary THA in the other two groups; 22 patients had previously undergone primary THA through a direct lateral approach (involving sectioning of the GMED tendon), 24 patients had previously undergone primary THA through a posterior approach (leaving the GMED tendon intact), 29 patients had primary hip OA, and 25 patients who suffered a femoral neck fracture served as controls. Biopsies from the GMED tendon were obtained at the time of the primary THA or the hip revision surgery. The tendon biopsies were examined ultrastructurally and histologically.<br><br> <i>Results</i> - Ultrastructurally, the direct lateral and posterior revision groups had statistically significantly more collagen fibrils with smaller diameters compared with the fracture and primary THA groups. Moreover, the direct lateral revision group had more collagen fibrils with smaller diameters compared with the posterior revision group.<br><br> Histologically, the direct lateral revision group had a higher total degeneration score (TDS) compared with the primary hip OA group.<br><br> <i>Conclusions</i> - The GMED tendon shows more ultrastructural degeneration in patients who undergo hip revision arthroplasty than in patients with primary OA of the hip and control patients, who had suffered a femoral neck fracture. Furthermore, patients who had previously undergone primary THA through a direct lateral approach revealed more histological GMED tendon degeneration than patients who suffer primary hip OA.en_US
dc.identifier.citationIbrahim, Hedlundh, Sernert, Meknas, Haag, Movin, Papadogiannakis, Kartus. Histological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplasty. Journal of Orthopaedic Surgery and Research. 2021;16en_US
dc.identifier.cristinIDFRIDAID 1918409
dc.identifier.doi10.1186/s13018-021-02434-1
dc.identifier.issn1749-799X
dc.identifier.urihttps://hdl.handle.net/10037/22431
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalJournal of Orthopaedic Surgery and Research
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700en_US
dc.subjectVDP::Medisinske Fag: 700en_US
dc.titleHistological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplastyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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