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dc.contributor.authorBirch, Stephen
dc.contributor.authorLee, Myeong Soo
dc.contributor.authorKim, Tae-Hun
dc.contributor.authorAlræk, Terje
dc.date.accessioned2021-10-12T08:06:05Z
dc.date.available2021-10-12T08:06:05Z
dc.date.issued2021-04-02
dc.description.abstract<i>Background</i> - Trials of acupuncture in the West began before textbooks about acupuncture were generally available. This placed trials at risk of possible faulty assumptions about the practice of acupuncture and adoption of problematic research assumptions and methods. Further, this lack of information has had an influence on the theories of developing a valid and reliable sham control treatment in clinical trials of acupuncture. This commentary explores these issues.<br><br> <i>Methods</i> - Literature review focussing on the time line of developments in the field, developments of sham interventions and use thereof and knowledge of physiological effects of needling.<br><br> <i>Results</i> - Early trials demonstrated a lack of knowledge about acupuncture. As the methodology of trials improved, new sham treatment methods were developed and adopted; however, the sham treatment methods were implemented without physiological studies exploring their potential physiological effects and without examining the broader practice of acupuncture internationally.<br><br> <i>Conclusions</i> - Mistaken assumptions about the practice of acupuncture reinforced by paucity of physiological investigations are factors that led to use of inappropriate sham interventions for acupuncture trials. These not only lead to confusing or misleading trial results, they, as far as we can see underestimate the effects of acupuncture leading to bias against acupuncture. There are significant problems with sham interventions and how they are applied in trials of acupuncture. Further research is needed to explore the effects of this both for future trials and for interpreting existing evidence.en_US
dc.identifier.citationBirch S, Lee MS, Kim T, Alræk T. Historical perspectives on using sham acupuncture in acupuncture clinical trials. Integrative Medicine Research (IMR). 2021;11:100725(1):1-6en_US
dc.identifier.cristinIDFRIDAID 1928661
dc.identifier.doi10.1016/j.imr.2021.100725
dc.identifier.issn2213-4220
dc.identifier.issn2213-4239
dc.identifier.urihttps://hdl.handle.net/10037/22750
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalIntegrative Medicine Research (IMR)
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en_US
dc.titleHistorical perspectives on using sham acupuncture in acupuncture clinical trialsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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