Vis enkel innførsel

dc.contributor.authorda Silva, Marisa Eleonor
dc.contributor.authorLaaksonen, Maarit A.
dc.contributor.authorLissner, Lauren
dc.contributor.authorWeiderpass, Elisabete
dc.contributor.authorRylander, Charlotta
dc.date.accessioned2022-01-25T10:19:26Z
dc.date.available2022-01-25T10:19:26Z
dc.date.issued2021-02-15
dc.description.abstractThere is a lack of tangible measures for directed public health action to halt the increase in weight and cancer. We estimated the fraction and preventable cases of all and major body fatness-related cancers attributable to 7-years weight gain (≥ 2 kg). We assessed validated self-reported anthropometrics from 44,114 women aged 34–49 years at the enrolment in 1991–1992 and from a second questionnaire in 1998, with follow-up through December 31, 2015. Over 18 years, 3216 body fatness-related cancers and 2041 deaths were reported. Nearly 70% of women experienced weight gain and the average weight change was 4 kg. We observed a substantial proportional impact of weight gain on pancreatic cancer with a population attributable fraction (PAF) of 41.8% (95% CI 8.1–63.1) and a high absolute impact on postmenopausal breast cancer with 4403 preventable cases (95% CI 1064–7299) and a PAF of 16.8% (95% CI 4.1–27.8), and colorectal cancer with 3857 preventable cases (95% CI 1313–5990) and a PAF of 22.6% (95% CI 7.7–35.1). Avoiding weight gain over seven years in middle adulthood could have prevented a considerable proportion of the cancer burden and thousands of cancer cases in women in Norway.en_US
dc.identifier.citationda Silva, Laaksonen, Lissner, Weiderpass, Rylander. Preventable fractions of cancer incidence attributable to 7-years weight gain in the Norwegian Women and Cancer (NOWAC) study. Scientific Reports. 2021;11(1)en_US
dc.identifier.cristinIDFRIDAID 1981766
dc.identifier.doi10.1038/s41598-021-83027-0
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/10037/23797
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.relation.journalScientific Reports
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.titlePreventable fractions of cancer incidence attributable to 7-years weight gain in the Norwegian Women and Cancer (NOWAC) studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel