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dc.contributor.authorRinaldo, Christine Hanssen
dc.contributor.authorNymo, Ingebjørg Helena
dc.contributor.authorSanchez Romano, Javier
dc.contributor.authorBreines, Eva Marie
dc.contributor.authorMurguzur, Francisco Javier Ancin
dc.contributor.authorTryland, Morten
dc.date.accessioned2022-02-18T11:51:07Z
dc.date.available2022-02-18T11:51:07Z
dc.date.issued2021-11-25
dc.description.abstractHepatitis E virus (HEV) is a common cause of viral hepatitis in humans. In developing countries, HEV-infections seem to be mainly associated with pigs, but other animal species may be involved in viral transmission. Recently, anti-HEV antibodies were detected in Norwegian wild reindeer. Here, we investigated anti-HEV seroprevalence in Norwegian semi-domesticated reindeer, animals in closer contact with humans than their wild counterparts. Blood samples (n = 516) were obtained from eight reindeer herds during the period 2013–2017 and analysed with a commercial enzyme-linked immunosorbent assay designed for detecting anti-HEV antibodies in livestock. Antibodies were found in all herds and for all sampling seasons. The overall seroprevalence was 15.7% (81/516), with adults showing a slightly higher seroprevalence (18.0%, 46/256) than calves (13.5%, 35/260, p = 0.11). The seroprevalence was not influenced by gender or latitude, and there was no temporal trend (p > 0.15). A positive association between the presence of anti-HEV antibodies and antibodies against alphaherpesvirus and pestivirus, detected in a previous screening, was found (p < 0.05). We conclude that Norwegian semi-domesticated reindeer are exposed to HEV or an antigenically similar virus. Whether the virus is affecting reindeer health or infects humans and poses a threat for human health remains unknown and warrants further investigations.en_US
dc.identifier.citationRinaldo CH, Nymo IH, Sanchez Romano J, Breines EM, Murguzur F, Tryland M. Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway. Pathogens. 2021;10(12):1-12en_US
dc.identifier.cristinIDFRIDAID 1969412
dc.identifier.doi10.3390/pathogens10121542
dc.identifier.issn2076-0817
dc.identifier.urihttps://hdl.handle.net/10037/24087
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalPathogens
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.titleSerological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norwayen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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