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dc.contributor.authorGhiasvand, Reza
dc.contributor.authorGreen, Adele C.
dc.contributor.authorSandanger, Torkjel M
dc.contributor.authorWeiderpass, Elisabete
dc.contributor.authorRobsahm, Trude Eid
dc.contributor.authorVeierød, Marit Bragelien
dc.date.accessioned2022-03-03T11:39:11Z
dc.date.available2022-03-03T11:39:11Z
dc.date.issued2021-04-21
dc.description.abstractPatients’ phenotypic characteristics might be associated with melanoma aggressiveness, but the evidence is scarce. This study examined the associations be­tween pigmentary characteristics, naevi and melanoma thickness. Data from the Norwegian Women and Cancer (NOWAC) study were analysed. By 2014, 1,243 women were diagnosed with a primary melanoma, and 1,140 had information on thickness. Using ordinal logistic regression models, the probability of being diagnosed with a specific thickness category was calculated by pigmentary score and naevi. Fair pigmentary score was associated with thinner trunk melanomas (probabilities of being diagnosed with a tumour ≤1.0 mm thickness were 74%, 66%, and 51% for fair, medium and dark pigmentary scores, respectively), but not the other sites. High number of naevi was associated with thicker nodular melanoma (NM) but not with super­ficial spreading melanoma. These findings suggest the need for greater overall vigilance and skin checks among women with fair pigmentary score. The association between naevi and NM suggest possible biological mechanisms.en_US
dc.identifier.citationGhiasvand R, Green AC, Sandanger TM, Weiderpass E, Robsahm R, Veierød MB. Phenotypic Characteristics and Melanoma Thickness in Women.. Acta Dermato-Venereologica. 2021;101en_US
dc.identifier.cristinIDFRIDAID 1989182
dc.identifier.doi10.2340/00015555-3806
dc.identifier.issn0001-5555
dc.identifier.issn1651-2057
dc.identifier.urihttps://hdl.handle.net/10037/24246
dc.language.isoengen_US
dc.publisherSociety for Publication of Acta Dermato-Venereologicaen_US
dc.relation.journalActa Dermato-Venereologica
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.titlePhenotypic Characteristics and Melanoma Thickness in Women.en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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