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dc.contributor.authorRomano, Giovanna
dc.contributor.authorAlmeida, Mariana
dc.contributor.authorCoelho, Ana Varela
dc.contributor.authorCutignano, Adele
dc.contributor.authorGoncalves, Lous G
dc.contributor.authorHansen, Espen Holst
dc.contributor.authorKhnykin, Denis
dc.contributor.authorMass, Tali
dc.contributor.authorRamšak, Andreja
dc.contributor.authorRocha, Miguel S.
dc.contributor.authorSilva, Tiago H.
dc.contributor.authorSugni, Michela
dc.contributor.authorBallarin, Loriano
dc.contributor.authorGenevière, Anne-Marie
dc.date.accessioned2022-03-24T08:57:07Z
dc.date.available2022-03-24T08:57:07Z
dc.date.issued2022-03-22
dc.description.abstractAquatic invertebrates are a major source of biomaterials and bioactive natural products that can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling products and biomaterials. Symbiotic microorganisms are often the real producers of many secondary metabolites initially isolated from marine invertebrates; however, a certain number of them are actually synthesized by the macro-organisms. In this review, we analysed the literature of the years 2010–2019 on natural products (bioactive molecules and biomaterials) from the main phyla of marine invertebrates explored so far, including sponges, cnidarians, molluscs, echinoderms and ascidians, and present relevant examples of natural products of interest to public and private stakeholders. We also describe omics tools that have been more relevant in identifying and understanding mechanisms and processes underlying the biosynthesis of secondary metabolites in marine invertebrates. Since there is increasing attention on finding new solutions for a sustainable large-scale supply of bioactive compounds, we propose that a possible improvement in the biodiscovery pipeline might also come from the study and utilization of aquatic invertebrate stem cellsen_US
dc.identifier.citationRomano, Almeida, Coelho, Cutignano, Goncalves, Hansen, Khnykin, Mass, Ramšak, Rocha, Silva, Sugni, Ballarin, Genevière. Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications. Marine Drugs. 2022en_US
dc.identifier.cristinIDFRIDAID 2011982
dc.identifier.doi10.3390/md20040219
dc.identifier.issn1660-3397
dc.identifier.urihttps://hdl.handle.net/10037/24526
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalMarine Drugs
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.titleBiomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applicationsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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