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dc.contributor.authorLinde, Jørgen Erland
dc.contributor.authorSolevåg, Anne Lee
dc.contributor.authorEilevstjønn, Joar
dc.contributor.authorBlacy, Ladislaus
dc.contributor.authorKidanto, Hussein
dc.contributor.authorErsdal, Hege Langli
dc.contributor.authorKlingenberg, Claus Andreas
dc.date.accessioned2022-04-05T06:08:49Z
dc.date.available2022-04-05T06:08:49Z
dc.date.issued2022-01-03
dc.description.abstractBackground: ST-segment changes to the fetal electrocardiogram (ECG) may indicate fetal acidosis. No large-scale characterization of ECG morphology immediately after birth has been performed, but ECG is used for heart rate (HR) assessment. We aimed to investigate ECG morphology immediately after birth in asphyxiated infants, using one-lead dry-electrode ECG developed for HR measurement. Methods: Observational study in Tanzania, between 2013–2018. Near-term and term infants that received bag-mask ventilation (BMV), and healthy controls, were monitored with one-lead dry-electrode ECG with a non-diagnostic bandwidth. ECGs were classified as normal, with ST-elevations or other ST-segment abnormalities including a biphasic ST-segment. We analyzed ECG morphology in relation to perinatal variables or short-term outcomes. Results: A total of 494 resuscitated and 25 healthy infants were included. ST-elevations were commonly seen both in healthy infants (7/25; 28%) and resuscitated (320/494; 65%) infants. The apparent ST-elevations were not associated with perinatal variables or short-term outcomes. Among the 32 (6.4%) resuscitated infants with “other ST-segment abnormalities”, duration of BMV was longer, 1-min Apgar score lower and normal outcomes less frequent than in the resuscitated infants with normal ECG or ST-elevations. Conclusions: ST-segment elevation was commonly seen and not associated with negative outcomes when using one-lead dry-electrode ECG. Other ST-segment abnormalities were associated with prolonged BMV and worse outcome. ECG with appropriate bandwidth and automated analysis may potentially in the future aid in the identification of severely asphyxiated infants.en_US
dc.identifier.citationLinde JE, Solevåg AL, Eilevstjønn J, Blacy L, Kidanto H, Ersdal HL, Klingenberg C. Delivery Room ST Segment Analysis to Predict Short Term Outcomes in Near-Term and Term Newborns. Children. 2022en_US
dc.identifier.cristinIDFRIDAID 2015032
dc.identifier.doi10.3390/children9010054
dc.identifier.issn2227-9067
dc.identifier.urihttps://hdl.handle.net/10037/24707
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalChildren
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.titleDelivery Room ST Segment Analysis to Predict Short Term Outcomes in Near-Term and Term Newbornsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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