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dc.contributor.advisorKilvær, Thomas Karsten
dc.contributor.authorWang, Kevin Johan
dc.date.accessioned2022-09-05T07:29:27Z
dc.date.available2022-09-05T07:29:27Z
dc.date.issued2020-08-31
dc.description.abstractResearch goal: To compare the survival outcomes, and patterns of loco-regional and metastatic recurrence of patients treated with primary radiotherapy for H&N cancer in different time periods where either conventional IGRT, IMRT or VMAT were available. Introduction: Conformal techniques are attractive for treating H&N cancer as fields may be shaped to spare critical organs. As a result, H&N cancer emerged as one of the first standard indications of IMRT/VMAT when these techniques became available. However, there exists few studies which evaluates patterns of recurrences. Methods: 292 patients receiving definitive radiotherapy for H&N cancer at the Department of Oncology at UNN Tromso between 2005-2015 were included. Patients were grouped according to available treatment technique (IGRT, IMRT and VMAT). Overall, disease-specific, loco-regional failure free and metastasis free survival were compared. Results: Our study suggests a slightly longer loco-regional recurrence free survival (p=0,066) in the period IMRT/VMAT were available, compared to when only 3D-IGRT was available. However, increased understanding of the tumor biology and the introduction of advanced diagnostic tools during the study period, precludes a definitive conclusion. Overall survival.en_US
dc.identifier.urihttps://hdl.handle.net/10037/26609
dc.language.isoengen_US
dc.publisherUiT Norges arktiske universiteten_US
dc.publisherUiT The Arctic University of Norwayen_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0en_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)en_US
dc.subject.courseIDMED-3950
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762en_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762en_US
dc.subjectRadiotherapyen_US
dc.titleVolumetric Arc Therapy versus Conventional Image Guided Radiotherapy in Head and Neck Cancer Patientsen_US
dc.typeMaster thesisen_US
dc.typeMastergradsoppgaveen_US


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Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
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