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dc.contributor.authorJohansen, Tonje Okkenhaug
dc.contributor.authorVangen-Lønne, Vetle
dc.contributor.authorHolmberg, Siril Therese
dc.contributor.authorSalvesen, Øyvind
dc.contributor.authorSolberg, Tore
dc.contributor.authorGulati, Agnete Malm
dc.contributor.authorNygaard, Øystein Petter
dc.contributor.authorGulati, Sasha
dc.date.accessioned2022-11-21T13:07:02Z
dc.date.available2022-11-21T13:07:02Z
dc.date.issued2022-07-19
dc.description.abstractBackground - The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year.<p> <p>Methods - Data were obtained from the Norwegian Registry for Spine Surgery (NORspine). Among 651 patients included, 177 (27.2%) were ≥ 70 years old. The primary outcome was change in the Neck Disability Index (NDI). Secondary outcomes were changes in the European Myelopathy Score (EMS), quality of life (EuroQoL EQ-5D), numeric rating scales (NRS) for headache, neck pain, and arm pain, and complications.<p> <p>Results - Significant improvements in all patient-reported outcomes (PROMs) were detected for both age cohorts at 1 year. For the two age cohorts combined, there was a statistically significant improvement in the NDI score (mean 9.2, 95% CI 7.7 to 10.6, P < 0.001). There were no differences between age cohorts in mean change of NDI (− 8.9 vs. − 10.1, P = 0.48), EQ-5D (0.13 vs. 0.17, P = 0.37), or NRS pain scores, but elderly patients experienced a larger improvement in EMS (0.7 vs. 1.3, P = 0.02). A total of 74 patients (15.6%) in the younger cohort and 43 patients (24.3%) in the older cohort experienced complications or adverse effects within 3 months of surgery, mainly urinary and respiratory tract infections.<p> <p>Conclusion - Surgery for DCM was associated with significant improvement across a wide range of PROMs for both younger and elderly patients. Surgery for DCM should not be denied based on age alone.en_US
dc.identifier.citationJohansen, Vangen-Lønne, Holmberg, Salvesen, Solberg, Gulati, Nygaard, Gulati. Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes. Acta Neurochirurgica. 2022en_US
dc.identifier.cristinIDFRIDAID 2044147
dc.identifier.doi10.1007/s00701-022-05282-y
dc.identifier.issn0001-6268
dc.identifier.issn0942-0940
dc.identifier.urihttps://hdl.handle.net/10037/27443
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.relation.journalActa Neurochirurgica
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleSurgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomesen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)