dc.contributor.author | Johansen, Tonje Okkenhaug | |
dc.contributor.author | Vangen-Lønne, Vetle | |
dc.contributor.author | Holmberg, Siril Therese | |
dc.contributor.author | Salvesen, Øyvind | |
dc.contributor.author | Solberg, Tore | |
dc.contributor.author | Gulati, Agnete Malm | |
dc.contributor.author | Nygaard, Øystein Petter | |
dc.contributor.author | Gulati, Sasha | |
dc.date.accessioned | 2022-11-21T13:07:02Z | |
dc.date.available | 2022-11-21T13:07:02Z | |
dc.date.issued | 2022-07-19 | |
dc.description.abstract | Background - The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year.<p>
<p>Methods - Data were obtained from the Norwegian Registry for Spine Surgery (NORspine). Among 651 patients included, 177 (27.2%) were ≥ 70 years old. The primary outcome was change in the Neck Disability Index (NDI). Secondary outcomes were changes in the European Myelopathy Score (EMS), quality of life (EuroQoL EQ-5D), numeric rating scales (NRS) for headache, neck pain, and arm pain, and complications.<p>
<p>Results - Significant improvements in all patient-reported outcomes (PROMs) were detected for both age cohorts at 1 year. For the two age cohorts combined, there was a statistically significant improvement in the NDI score (mean 9.2, 95% CI 7.7 to 10.6, P < 0.001). There were no differences between age cohorts in mean change of NDI (− 8.9 vs. − 10.1, P = 0.48), EQ-5D (0.13 vs. 0.17, P = 0.37), or NRS pain scores, but elderly patients experienced a larger improvement in EMS (0.7 vs. 1.3, P = 0.02). A total of 74 patients (15.6%) in the younger cohort and 43 patients (24.3%) in the older cohort experienced complications or adverse effects within 3 months of surgery, mainly urinary and respiratory tract infections.<p>
<p>Conclusion - Surgery for DCM was associated with significant improvement across a wide range of PROMs for both younger and elderly patients. Surgery for DCM should not be denied based on age alone. | en_US |
dc.identifier.citation | Johansen, Vangen-Lønne, Holmberg, Salvesen, Solberg, Gulati, Nygaard, Gulati. Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes. Acta Neurochirurgica. 2022 | en_US |
dc.identifier.cristinID | FRIDAID 2044147 | |
dc.identifier.doi | 10.1007/s00701-022-05282-y | |
dc.identifier.issn | 0001-6268 | |
dc.identifier.issn | 0942-0940 | |
dc.identifier.uri | https://hdl.handle.net/10037/27443 | |
dc.language.iso | eng | en_US |
dc.publisher | Springer | en_US |
dc.relation.journal | Acta Neurochirurgica | |
dc.rights.accessRights | openAccess | en_US |
dc.rights.holder | Copyright 2022 The Author(s) | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | en_US |
dc.rights | Attribution 4.0 International (CC BY 4.0) | en_US |
dc.title | Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes | en_US |
dc.type.version | publishedVersion | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |