Browsing Doktorgradsavhandlinger (NT-fak) by Author "Thakkar, Balmukund"
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A Biofocussed Chemoprospecting Approach to Drug Discovery: Design, Synthesis and Bioactivity Screening of Diverse Biofocussed Chemical Libraries
Thakkar, Balmukund (Doctoral thesis; Doktorgradsavhandling, 2017-04-28)With pharma R & D witnessing rising cost, high attrition rates and an overall decline in productivity in recent times, newer approaches are needed for more efficient early phase drug discovery. This thesis describes a new approach, “biofocussed chemoprospecting”. The essence of the approach is to use diverse, yet “bio-like” compounds for efficient hit-finding, along with property filtering and ...