Doktorgradsavhandlinger (NT-fak): Recent submissions
Now showing items 241-260 of 305
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Multiscale Methods for Statistical Inference on Regular Lattice Data
(Doctoral thesis; Doktorgradsavhandling, 2013-12-13)This thesis presents methods for multiscale statistical inference on random fields on a regular two-dimensional lattice. There are two distinct concepts of scale that are used in the thesis. The first one is connected to the computer vision community's understanding of scale-space as a family of smooths of a digital image, with fine structure being revealed at low levels of smoothing and the coarser ... -
What are the characteristics of mathematical creativity? An empirical and theoretical investigation of mathematical creativity.
(Doctoral thesis; Doktorgradsavhandling, 2013-12-17)The main research question in this research project was "what are the characteristics of mathematical creativity?" It was investigated both qualitatively and quantitatively and the findings are presented in four articles. In the first article, three high achieving students were given an unfamiliar trigonometric problem. The findings indicate strongly that the student’s way of thinking is strongly ... -
Recursive calculation of high-order molecular response properties
(Doctoral thesis; Doktorgradsavhandling, 2013-12-06)This thesis presents the implementation and application of a computer program for the open-ended calculation of response properties of molecular systems. Using recursive programming techniques, a recently published formulation of response theory can be implemented in a manner that allows the calculation of response properties to arbitrary order. The limitations of the code are dictated by the ... -
Benthic foraminifera as indicators of natural variability and anthropogenic impact
(Doctoral thesis; Doktorgradsavhandling, 2013-11-28)Benthic foraminifera (micro-organism living on the sea-floor) were studied in the southwestern Barents Sea and Hammerfest harbor. The study focused on the response of the micro-organisms to natural and man made environmental changes. The study shows that the southwestern Barents sea is relatively clean, and the foraminifera are only impacted by natural changes. However, in the Hammerfest harbor, ... -
Model-Driven Software Development for Continuity of Care Information Systems - Toolchain design and evaluation
(Doctoral thesis; Doktorgradsavhandling, 2013-03-13)This thesis summarizes six years of design, development and evaluation of a model- driven development toolchain and design of software services for continuity of care. The overall research method has been design science, with a strong focus on creating and evaluating the core artefact: the ModelHealth Toolchain. Three iterations with toolchain design and assessments were deemed necessary to be able ... -
Strength and rheological evolution of the lower continental crust: an experimental study of the deformation behavior of feldspar and quartz at high pressure and temperature
(Doctoral thesis; Doktorgradsavhandling, 2013-09-10)Models representing the strength of the lithosphere (i.e. strength-depth profiles) are mainly based on the rheological properties of the minerals quartz and feldspar that, to a large extent, are determined in laboratory-based rock deformation studies. The study of the deformation behavior of quartz and feldspar is of fundamental importance for the understanding and modeling of plate tectonics and ... -
From being interrupted by mobile devices to CallMeSmart: A context-sensitive communication system for mobile communication in hospitals
(Doctoral thesis; Doktorgradsavhandling, 2013-08-22)Wireless communication infrastructure in hospitals represents a core for information sharing between health care workers. Medical staff’s work situation is highly mobile, and important information is constantly shared between co-workers to provide high quality services to the patients. To be able to communicate at any place and at any time during shifts, physicians carry mobile communication devices, ... -
Mass-movements on the continental slope offshore Lofoten, Northern Norway
(Doctoral thesis; Doktorgradsavhandling, 2013-09-20)Swath bathymetry, side-scan sonar, sub-bottom profiler and seismic data from the continental slope offshore the Lofoten Islands, northern Norway reveal smaller-scale mass movements in water depths between 1100 and 2500 m. These mass movements have volumes of 0.061 to 8.7 km3 and are interpreted as translational slides involving spreading and multi-phase retrogression. The spatial variation in failure ... -
Distribution, depositional environment and post-depositional deformation of Cenozoic gravity-induced deposits along the western Barents Sea continental margin
(Doctoral thesis; Doktorgradsavhandling, 2013-10-01)Arktis er en av de få gjenværende, geologisk minst undersøkte, områdene i verden, hvor den norske kontinentalmarginen i Barentshavet nå blir undersøkt og har både vitenskapelig og industriell interesse. Formålet med doktorgradsavhandlingen er å få en bedre forståelse av interne og eksterne karakteristikker, utbredelse i rom og tid, sedimentasjonsmiljø og deformasjonsgrad av kenozoiske dypmarine ... -
Statistical Analysis of Lattice Data with Wavelet Variance Methods and Spatiotemporal Modeling of Infectious Disease Spread
(Doctoral thesis; Doktorgradsavhandling, 2013-06-26)The focus of this thesis is the analysis of both regular and irregular lattice data, described in three papers. Paper I presents an extension of the pyramid algorithm for efficient Maximal Overlap Discrete Wavelet Transform coefficient calculation. As opposed to common usage of two-dimensional wavelet decomposition, it here also allows for different scales in the vertical and horizontal direction. ... -
Development of novel renin inhibitors and interaction of antimicrobial and cytotoxic peptides with plasma proteins. A drug discovery study
(Doctoral thesis; Doktorgradsavhandling, 2013-06-14)In this study we have explored the structure activity relationship of molecules with potential as novel drug classes toward current medical challenges as hypertension, cancer and infections caused by antibiotic resistant bacteria. Direct renin inhibitors have for a long time been an interesting group of potential anti-hypertension drugs, as they inhibit the first and rate-limiting step in the signal ... -
Multitemporal Analysis of Multipolarization Synthetic Aperture Radar Images for Robust Surface Change Detection
(Doctoral thesis; Doktorgradsavhandling, 2013-06-07)This thesis addresses two approaches for change detection from multipolarization, multilooked SAR images: a post-classification comparison and a direct change detection. We consider the complete workflow associated with performing post-classification change detection from time series of multipolarization SAR (PolSAR) images acquired with different imaging geometries and polarimetric configurations. ... -
Acyl homoserine lactone signaling in members of the Vibrionaceae family
(Doctoral thesis; Doktorgradsavhandling, 2013-06-13)Bacterial cell to cell communication, which involves regulation of gene expression in response to cell density, is defined as Quorum Sensing (QS). In QS small molecule signals are produced, which regulate their own production and are defined as auto-inducers. These signals are received by receiver proteins and in response certain genes are regulated directly or indirectly by these receiver proteins. ... -
Optical Forces, Waveguides and Micro Raman Spectroscopy
(Doctoral thesis; Doktorgradsavhandling, 2012-12-21)Optical waveguides are used to confine propagating light. In a dielectric waveguide, a small part of the propagating light travels along and just outside the waveguide surface. This evanescent field can interact with objects on the waveguide surface. Two effects of this light-matter interaction are presented, optical forces and Raman scattering. Optical forces are caused by changes in the momentum ... -
Geophysical characterizations of fluid flow and gas-hydrate systems of the NW-Svalbard and SW-Barents Sea margins
(Doctoral thesis; Doktorgradsavhandling, 2013-02-06)The thesis consists of four parts and its four main objectives are: (1) to establish a potential link between serpentinization beneath a young sedimented-ocean ridge and carbon release and gas hydrate formation directly above it, (2) to understand the coexistence of free gas and gas-hydrate and to image the geophysical evidence for a geologically controlled gas hydrate, fluid migration pathway and ... -
Understanding and predicting one- and two-photon absorption properties of molecular complexes
(Doctoral thesis; Doktorgradsavhandling, 2013-01-22)This thesis presents the development of theoretical models for the calculations of one- and two-photon absorption, and computational studies on solvated systems and biomolecules. The photon-absorbing chromophore is described by density functional theory, while the effects of the surroundings are taken into account by means of polarizable embedding models. The theory and implementation of a three-layered ... -
Ice Shelf - Ocean Interaction in the Eastern Weddell Sea, Antarctica
(Doctoral thesis; Doktorgradsavhandling, 2012-12-10)This thesis investigates the interaction of the Antarctic ice shelves along the coast of Dronning Maud Land with the ocean circulation in the Eastern Weddell Sea. A set of direct oceanic observations below the Fimbul Ice Shelf, which were acquired during three Antarctic field seasons in the austral summers 2009/10, 2010/11 and 2011/12, is a central element of the presented work. This new oceanographic ... -
Processes and dynamics during deglaciation of a polar continental shelf. Examples from the marine-based Barents Sea Ice Sheet
(Doctoral thesis; Doktorgradsavhandling, 2012-12-20)The main objective of this PhD thesis was to reconstruct the pattern and main processes of the last deglaciation of the Barents Sea Ice Sheet. The thesis consists of an introductory part and five papers. The conclusions presented in the papers were based on data acquired with a suite of marine geophysical and geological methods, including multibeam-swath bathymetry data, chirp data, airgun and sparker ... -
Design, Synthesis and Biological Activity of Small α-Aminoboron Containing Peptidomimetics
(Doctoral thesis; Doktorgradsavhandling, 2013-01-18)Antimicrobial peptides (AMPs) are a special group of small amphipathic peptides (which hold both hydrophilic and hydrophobic regions) composed of different amino acids and produced by all living organisms as a part of innate immunity. With the increasing microbial resistance to traditional antibiotics the need for unconventional therapeutic has become crucial. This thesis deals with the design ... -
Display Scale in a ‘Document’ perspective : size matters
(Doctoral thesis; Doktorgradsavhandling, 2012-11-26)The work summarized in this thesis has its basis in technology to support human collaboration. I have investigated how large, high-resolution display (LaHiRD) technology, implemented using display wall technology (large, tiled displays implemented as one coherent display surface) could support clinical work. Hence, I have worked with the topic of technological support for human collaboration (or ...