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dc.contributor.authorHolvik, Kristin
dc.contributor.authorEllingsen, Christian Lycke
dc.contributor.authorSolbakken, Siri Marie
dc.contributor.authorFinnes, Trine Elisabeth
dc.contributor.authorTalsnes, Ove
dc.contributor.authorGrimnes, Guri
dc.contributor.authorTell, Grethe Seppola
dc.contributor.authorSøgaard, Anne-Johanne
dc.contributor.authorMeyer, Haakon Eduard
dc.date.accessioned2023-05-03T08:26:52Z
dc.date.available2023-05-03T08:26:52Z
dc.date.issued2023-03-31
dc.description.abstractBackground Information on cause of death may help appraise the degree to which the high excess mortality after hip fracture refects pre-existing comorbidities or the injury itself. We aimed to describe causes of death and causespecifc excess mortality through the frst year after hip fracture.<p> <p>Methods For studying the distribution of causes of death by time after hip fracture, we calculated age-adjusted cause-specifc mortality at 1, 3, 6 and 12 months in patients hospitalized with hip fracture in Norway 1999–2016. Underlying causes of death were obtained from the Norwegian Cause of Death Registry and grouped by the Euro‑ pean Shortlist for Causes of Death. For estimating excess mortality, we performed fexible parametric survival analyses comparing mortality hazard in patients with hip fracture (2002–2017) with that of age- and sex matched controls drawn from the Population and Housing Census 2001. <p>Results Of 146,132 Norwegians with a frst hip fracture, a total of 35,498 (24.3%) died within one year. By 30 days post-fracture, external causes (mainly the fall causing the fracture) were the underlying cause for 53.8% of deaths, fol‑ lowed by circulatory diseases (19.8%), neoplasms (9.4%), respiratory diseases (5.7%), mental and behavioural disorders (2.0%) and diseases of the nervous system (1.3%). By one-year post-fracture, external causes and circulatory diseases together accounted for approximately half of deaths (26.1% and 27.0%, respectively). In the period 2002–2017, causespecifc one-year relative mortality hazard in hip fracture patients vs. population controls ranged from 1.5 for circula‑ tory diseases to 2.5 for diseases of the nervous system in women, and correspondingly, from 2.4 to 5.3 in men. <p>Conclusions Hip fractures entail high excess mortality from all major causes of death. However, the traumatic injury of a hip fracture is the most frequently reported underlying cause of death among older patients who survive less than one year after their fracture.en_US
dc.identifier.citationHolvik, Ellingsen, Solbakken, Finnes, Talsnes, Grimnes, Tell, Søgaard, Meyer. Cause-specific excess mortality after hip fracture: the Norwegian Epidemiologic Osteoporosis Studies (NOREPOS). BMC Geriatrics. 2023;23(1)en_US
dc.identifier.cristinIDFRIDAID 2138888
dc.identifier.doi10.1186/s12877-023-03910-5
dc.identifier.issn1471-2318
dc.identifier.urihttps://hdl.handle.net/10037/29105
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalBMC Geriatrics
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleCause-specific excess mortality after hip fracture: the Norwegian Epidemiologic Osteoporosis Studies (NOREPOS)en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)