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dc.contributor.authorStelander, Line Tegner
dc.contributor.authorLorem, Geir F
dc.contributor.authorHøye, Anne
dc.contributor.authorBramness, Jørgen Gustav
dc.contributor.authorWynn, Rolf
dc.contributor.authorGrønli, Ole Kristian
dc.date.accessioned2023-05-05T10:38:31Z
dc.date.available2023-05-05T10:38:31Z
dc.date.issued2023-02-16
dc.description.abstractBackground Based on findings of increasing alcohol consumption in older adults, it is important to clarify the health consequences. Using data from the Tromsø study, we aimed to investigate the relationship between different levels of alcohol consumption in old adulthood and self-rated health trajectories and all-cause mortality.<p> <p>Methods This is an epidemiological study utilizing repeated measures from the Tromsø study cohort. It allows followup of participants from 1994 to 2020. A total of 24,590 observations of alcohol consumption were made in older adults aged 60–99 (53% women). Primary outcome measures: Self-rated health (SRH) and all-cause mortality. SRH was reported when attending the Tromsø study. Time of death was retrieved from the Norwegian Cause of Death Registry. The follow-up time extended from the age of study entry to the age of death or end of follow-up on November 25, 2020. Predictor: Average weekly alcohol consumption (non-drinker, <100g/week, ≥100g/week). We fitted two-level logistic random effects models to examine how alcohol consumption was related to SRH, and Cox proportional hazards models to examine its relation to all-cause mortality. Both models were stratifed by sex and adjusted for sociodemographic factors, pathology, biometrics, smoking and physical activity. In addition, all the confounders were examined for whether they moderate the relationship between alcohol and the health-related outcomes through interaction analyses. <p>Results We found that women who consumed ≥100g/week had better SRH than those who consumed <100g/ week; OR 1.85 (1.46–2.34). This pattern was not found in men OR 1.18 (0.99–1.42). We identifed an equal mortality risk in both women and men who exceeded 100g/week compared with those who consumed less than 100g/week; HR 0.95 (0.73–1.22) and HR 0.89 (0.77–1.03), respectively. <p>Conclusions There was no clear evidence of an independent negative effect on either self-rated health trajectories or all-cause mortality for exceeding an average of 100g/week compared to lower drinking levels in this study with up to 25 years follow-up. However, some sex-specifc risk factors in combination with the highest level of alcohol consumption led to adverse efects on self-rated health. In men it was the use of sleeping pills or tranquilisers and≥20 years of smoking, in women it was physical illness and older age.en_US
dc.identifier.citationStelander LTS, Lorem gfl, Høye A, Bramness JG, Wynn R, Grønli OK. The effects of exceeding low-risk drinking thresholds on self-rated health and all-cause mortality in older adults: The Tromsø Study 1994-2020. Archives of Public Health. 2023;81en_US
dc.identifier.cristinIDFRIDAID 2126480
dc.identifier.doi10.1186/s13690-023-01035-0
dc.identifier.issn0778-7367
dc.identifier.issn2049-3258
dc.identifier.urihttps://hdl.handle.net/10037/29124
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalArchives of Public Health
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleThe effects of exceeding low-risk drinking thresholds on self-rated health and all-cause mortality in older adults: The Tromsø Study 1994-2020en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)